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ICOSAPENT

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  AAN7QOV9EA

Status:
US Approved Rx (2023)
First approved in 2008
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
fatty acid beta-oxidation
4
GO:0004465 lipoprotein lipase activity
4
GO:0004144 diacylglycerol O-acyltransferase activity
4
Peroxisome proliferator-activated receptor gamma
111
lipoprotein oxidation
4
transformed cell apoptotic process
108
Receptor-mediated non-selective cation current (Icat)
4
Peroxisome proliferator-activated receptor delta
29
Prolyl endopeptidase
9
Cyclooxygenase-2
196
Conditions:
Hypertriglyceridemia
17
Major depressive disorder
173
Alzheimer’s disease
272
Icosapent is an important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardio...
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