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Showing 1 - 10 of 24 results

Status:
US Approved Rx (2020)
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)


Lactitol is a sugar alcohol. This ingredient has been determined to be GRAS for specified uses as a direct food additive and foods containing lactitol are eligible for a health claim related to dental caries. Lactitol is used as an oral powder or sol...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Melizame is a sugar substitute for sweetening caloric or noncaloric materials.
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)


Alitame [l-α-aspartyl-N-(2,2,4,4-tetramethyl-3-thioethanyl)-d-alaninamide] is an amino acid-based sweetener developed by Pfizer Central Research from l-aspartic acid, d-alanine, and 2,2,4,4-tetraethylthioethanyl amine. A terminal amide group instead ...
Status:
US Previously Marketed
First approved in 1953

Class (Stereo):
CHEMICAL (ACHIRAL)

CALCIUM CYCLAMATE, a salt of cyclamic acid, is an artificial sweetener. Cyclamates and its salts (such as calcium cyclamate, sodium cyclamate, magnesium cyclamate, and potassium cyclamate) are currently prohibited from use in the United States.
Status:
US Previously Marketed
First approved in 1950

Class (Stereo):
CHEMICAL (ACHIRAL)



Cyclamic acid (Cyclamate) is banned in the United States but it is used in many other Western countries without safety concerns. Cyclamate interacts with the sweet taste receptor subunit T1R3 transmembrane domain. Initially it was recommended for use...
Status:
US Previously Marketed
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Saccharin is the most established of the artificial sweeteners on the market, this mixture of dextrose and saccharin has been in use for over a century and is found in diet versions of soft drinks. It is 300-500 times sweeter than sugar and contains ...
Status:
Possibly Marketed Outside US
First approved in 2006

Class (Stereo):
CHEMICAL (ABSOLUTE)


Sucralose (sold commercially as Splenda), a water-soluble chlorocarbohydrate, is a sweetener used to sweeten food, beverages, medications, etc., such as sugar, saccharine or other low-calorie synthetic products. In the European Union, it is also kno...
Status:
Possibly Marketed Outside US
First approved in 2002

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Acesulfame is a non-nutritive sweetener Acesulfame potassium is a calorie-free artificial sweetener, also known as Acesulfame K or Ace K (K being the symbol for potassium), and marketed under the trade names Sunett and Sweet One. In the European Unio...
Status:
Possibly Marketed Outside US
First approved in 1995

Class (Stereo):
CHEMICAL (ABSOLUTE)



Aspartame (l-aspartyl-l-phenylalanine methyl ester) known to the public as NutraSweet has been the subject of controversy since it first became an ingredient in food products. The perceived sweetness of aspartame in humans is due to its binding of th...