Benzoylmesaconine (BMA) is the main Aconitum alkaloid in Radix Aconiti Lateralis Preparata. Notably, the high levels of toxicity of Radix Aconiti are derived from diester aconitum alkaloids, including aconitine, mesaconitine and hypaconitine, which can be hydrolyzed to benzoylaconine, benzoylmesaconine and benzoylhypaconine, respectively. Benzoylmesaconine exhibits biological effects, including analgesic, antiviral and antifungal activities.

Napelline is a diterpenoid alkaloid, from plants of the Aconitum genus, Ranunculaceae. It is a potent antiarrhythmic of class I with weak hypotensive and N-cholinoblocking effects. Napelline has analgesic and anti-inflammatory activity. Napelline has a stronger antiarrhythmic activity than Quinidine or Procaïnamide. 10(-4) - 10(-5) M block inward Na+ currents