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Showing 71 - 80 of 4,331 results

Status:
US Approved Rx (2014)
First approved in 1999

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


NEO 212 is novel DNA alkylating agent exhibiting superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo. NEO212 is a conjugate of temozolomide (TMZ,) with the natural product perillyl alcohol (POH...
Status:
US Approved Rx (2018)
First approved in 1999

Class (Stereo):
CHEMICAL (ACHIRAL)



Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. Bexarotene is a member of a subclass of retinoids that selectively ...
Status:
US Approved Rx (1998)
First approved in 1998

Class (Stereo):
CHEMICAL (ABSOLUTE)



PRIFTIN® (rifapentine) is indicated in adults and children 12 years and older for the treatment of active pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis. PRIFTIN must always be used in combination with one or more antituberculosis (...
Status:
US Approved Rx (2018)
First approved in 1998

Class (Stereo):
CHEMICAL (ABSOLUTE)



Capecitabine is a fluoropyrimidine carbamate with antineoplastic activity. It is an orally administered systemic prodrug which is converted to 5-fluorouracil (5-FU). Both normal and tumor cells metabolize 5-FU to 5-fluoro-2’-deoxyuridine monophosphat...
Status:
US Approved Rx (2006)
First approved in 1998

Class (Stereo):
CHEMICAL (RACEMIC)



Citalopram (brand names: Celexa, Cipramil, and others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has U.S. Food and Drug Administration approval to treat major depression,[2]which it received in 1998, and...
Status:
US Approved Rx (2020)
First approved in 1998

Class (Stereo):
CHEMICAL (ACHIRAL)



Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Celecoxib is an analgesic that is FDA approved for the treatment of osteoarthritis,rheumatoid arthritis,juvenile r...
Status:
US Approved Rx (2015)
First approved in 1998

Class (Stereo):
CHEMICAL (ABSOLUTE)



Montelukast (SINGULAIR®) is a selective and orally active leukotriene D4 (LTD4) receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor. It is indicated for the prophylaxis and chronic treatment of asthma, for prevention of exerci...
Status:
US Approved Rx (2012)
First approved in 1997

Class (Stereo):
CHEMICAL (ACHIRAL)



Quetiapine, marketed as SEROQUEL XR, is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and along with an antidepressant to treat major depressive disorder. The mechanism of action of SEROQUEL XR in the treatm...
Status:
US Approved Rx (2003)
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Nelfinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotei...
Status:
US Approved Rx (2016)
First approved in 1997

Class (Stereo):
CHEMICAL (ACHIRAL)



Raloxifene (marketed as Evista by Eli Lilly and Company) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. Raloxifene binds to estrogen receptors, resulti...