U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 771 - 780 of 18894 results

Status:
Investigational
Source:
INN:bexotegrast [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT01777165: Phase 2 Interventional Completed Acute Kidney Injury
(2013)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Modimelanotide is a melanocortinergic peptide drug derived from α-melanocyte-stimulating hormone (α-MSH) which was under development for the treatment of acute kidney injury. Modimelanotide had promising preclinical data, and a Phase II trial in patients undergoing cardiopulmonary bypass surgery showed a reduced incidence of acute kidney injury in subjects that received Modimelanotide. However, a Phase IIb, multicenter study of Modimelanotide in patients with chronic kidney disease who underwent cardiopulmonary bypass surgery failed to show a significant reduction in the incidence of acute kidney injury in subjects who received the drug, both by serum creatinine measurements and by novel biomarkers of tubular injury.
Status:
Investigational
Source:
INN:cenupatide [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00545454: Phase 2 Interventional Completed Rheumatoid Arthritis
(2007)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT01215864: Phase 1 Interventional Completed Advanced Solid Tumors
(2011)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT00572598: Early Phase 1 Interventional Completed Breast Cancer
(2005)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT02965599: Phase 2 Interventional Terminated Arthritis, Rheumatoid
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Status:
Investigational
Source:
NCT02490774: Phase 2 Interventional Terminated Contraception
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT03262389: Phase 2 Interventional Completed Multiple Myeloma
(2017)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

FLUDEOXYGLUCOSE is a fluorinated glucose analog. Its 18F radiolabelled form is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging.
Status:
Investigational
Source:
NCT01977443: Phase 2 Interventional Completed Viral Conjunctivitis
(2013)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)