FLUOROPACLITAXEL F-18

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C47H50FNO14
Molecular Weight	870.8991
Optical Activity	UNSPECIFIED
Defined Stereocenters	11 / 11
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C6=CC=C([18F])C=C6)C7=CC=CC=C7

InChI

InChIKey=ZWDPMBMJMPIWMJ-LDPXFCOMSA-N

InChI=1S/C47H50FNO14/c1-24-31(61-43(57)36(53)35(27-13-9-7-10-14-27)49-41(55)28-17-19-30(48)20-18-28)22-47(58)40(62-42(56)29-15-11-8-12-16-29)38-45(6,32(52)21-33-46(38,23-59-33)63-26(3)51)39(54)37(60-25(2)50)34(24)44(47,4)5/h7-20,31-33,35-38,40,52-53,58H,21-23H2,1-6H3,(H,49,55)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1/i48-1

HIDE SMILES / InChI

Molecular Formula	C47H50FNO14
Molecular Weight	870.8991
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	11 / 11
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Tue Apr 01 22:17:28 GMT 2025` Edited by `admin` on `Tue Apr 01 22:17:28 GMT 2025`
Record UNII	CHP2LM7KK2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUOROPACLITAXEL F-18

Common Name

English

4-(18F)FLUOROPACLITAXEL

Preferred Name

English

[F-18] fluoropaclitaxel

Common Name

English

BENZENEPROPANOIC ACID, .BETA.-((4-(FLUORO-18F)BENZOYL)AMINO)-.ALPHA.-HYDROXY-, (2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO

Systematic Name

English

4-FLUOROPACLITAXEL F-18

Common Name

English

FPAC F-18

Common Name

English

[18F]-FPAC

Common Name

English

Code System Code Type Description

PUBCHEM

5331135

Created by admin on Tue Apr 01 22:17:28 GMT 2025 , Edited by admin on Tue Apr 01 22:17:28 GMT 2025

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CAS

594848-00-7

Created by admin on Tue Apr 01 22:17:28 GMT 2025 , Edited by admin on Tue Apr 01 22:17:28 GMT 2025

PRIMARY

FDA UNII

CHP2LM7KK2

Created by admin on Tue Apr 01 22:17:28 GMT 2025 , Edited by admin on Tue Apr 01 22:17:28 GMT 2025

PRIMARY

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					CHP2LM7KK2

FLUOROPACLITAXEL F-18

ACTIVE MOIETY

Comments:

High 18F-FPAC uptake predicted tumor regression. This relationship was found for mice bearing xenografts from cell lines selected to be either sensitive or intrinsically resistant to paclitaxel in vitro.

Amount: