U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C6H11FO5
Molecular Weight 182.1472
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUDEOXYGLUCOSE

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O

InChI

InChIKey=AOYNUTHNTBLRMT-SLPGGIOYSA-N
InChI=1S/C6H11FO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1

HIDE SMILES / InChI
FLUDEOXYGLUCOSE is a fluorinated glucose analog. Its 18F radiolabelled form is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging.

Approval Year

PubMed

PubMed

TitleDatePubMed
The role of TSH for 18F-FDG-PET in the diagnosis of recurrence and metastases of differentiated thyroid carcinoma with elevated thyroglobulin and negative scan: a meta-analysis.
2010-08
Hypermetabolism in patients with dementia with Lewy bodies.
2010-07
Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase.
2010-07
Targeted therapies in renal cell cancer: recent developments in imaging.
2010-06
Effects of low-field magnetic stimulation on brain glucose metabolism.
2010-06
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
2010-04-20
Primary hepatic schwannoma mimicking malignancy on fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography.
2010-03
Pretargeted radioimmunotherapy in rapidly progressing, metastatic, medullary thyroid cancer.
2010-02-15
The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
2010-01
Diagnostic performance of fluorodeoxyglucose-positron emission tomography/computed tomography of breast cancer in detecting axillary lymph node metastasis: comparison with ultrasonography and contrast-enhanced CT.
2009-12
F-18 2-fluoro-2-deoxy-glucose positron emission tomography/computed tomography for the detection of radicular and peripheral neurolymphomatosis: correlation with magnetic resonance imaging and ultrasound.
2009-08
Evaluation of sorafenib treatment in metastatic renal cell carcinoma with 2-fluoro-2-deoxyglucose positron emission tomography and computed tomography.
2009-07
Chemical approaches to perturb, profile, and perceive glycans.
2009-06-16
Positive correlation between serum liver enzyme levels and standard uptake values of liver on FDG-PET.
2009-03-10
Combined FDG-PET/CT for the detection of unknown primary tumors: systematic review and meta-analysis.
2009-03
The role of FDG-PET in distinguishing between septic and aseptic loosening in hip prosthesis: a review of literature.
2009-02
Regional differences in the coupling between resting cerebral blood flow and metabolism may indicate action preparedness as a default state.
2009-02
Determination of indication for sentinel lymph node biopsy in clinical node-negative breast cancer using preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography fusion imaging.
2009-01
Noninvasive diagnosis of solitary pulmonary lesions in cancer patients based on 2-fluoro-2-deoxy-D-glucose avidity on positron emission tomography/computed tomography.
2008-12-01
Potential value of quantitative analysis of cerebral PET in early cognitive decline.
2008-11-13
The inhibitory effect of 2-halo derivatives of D-glucose on glycolysis and on the proliferation of the human malaria parasite Plasmodium falciparum.
2008-11
Superior antitumor efficiency of cisplatin-loaded nanoparticles by intratumoral delivery with decreased tumor metabolism rate.
2008-11
Positron Emission Tomography (PET) radiotracers in oncology--utility of 18F-Fluoro-deoxy-glucose (FDG)-PET in the management of patients with non-small-cell lung cancer (NSCLC).
2008-10-17
Inverse association between liver fat content and hepatic glucose uptake in patients with type 2 diabetes mellitus.
2008-10
Imaging in cutaneous melanoma.
2008-10
FDG uptake, a surrogate of tumour hypoxia?
2008-08
Synthesis and cytotoxic properties of new fluorodeoxyglucose-coupled chlorambucil derivatives.
2008-05-01
Simultaneous analysis of FDG, ClDG and Kryptofix 2.2.2 in [18F]FDG preparation by high-performance liquid chromatography with UV detection.
2008-02
Pulmonary echinococcosis mimicking multiple lung metastasis of breast cancer: the role of fluoro-deoxy-glucose positron emission tomography.
2008-01-21
The utility of FDG-PET in the preoperative staging of esophageal cancer.
2008
Combined approach of perioperative 18F-FDG PET/CT imaging and intraoperative 18F-FDG handheld gamma probe detection for tumor localization and verification of complete tumor resection in breast cancer.
2007-12-21
Prognostic Value of FDG-PET in patients with oropharyngeal carcinoma treated with concurrent chemoradiotherapy.
2007-11-16
Cervical node metastasis as the first sign of cancer of the caecum.
2007-11-02
Standardized uptake values for breast carcinomas assessed by fluorodeoxyglucose-positron emission tomography correlate with prognostic factors.
2007-11
The role of PET/CT for evaluating breast cancer.
2007-10-10
When is it best to repeat a 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography scan on patients with non-small cell lung cancer who have received neoadjuvant chemoradiotherapy?
2007-10
Stereotactic cortical resection in non-lesional extra-temporal partial epilepsy.
2007-10
Accessing the aortopulmonary window (#5) and the paraaortic (#6) lymph nodes in patients with non-small cell lung cancer.
2007-09
Case report: PET/CT, a cautionary tale.
2007-08-03
F-18 FDG PET in detecting uterine leiomyoma.
2007-06-10
FDG-PET for evaluating the antitumor effect of intraarterial 3-bromopyruvate administration in a rabbit VX2 liver tumor model.
2007-06-08
Nuclear medicine in the rehabilitative treatment evaluation in stroke recovery. Role of diaschisis resolution and cerebral reorganization.
2007-06
Early therapeutic response assessment by (18)FDG-positron emission tomography during chemotherapy in patients with diffuse large B-cell lymphoma: isolated residual positivity involving bone is not usually a predictor of subsequent treatment failure.
2007-03
Hypertrophic cardiomyopathy complicated by left ventricular apical necrosis and aneurysm in a young man: FDG-PET findings.
2007-03
A comparative study on the value of FDG-PET and sentinel node biopsy to identify occult axillary metastases.
2007-03
Risk-adapted BEACOPP regimen can reduce the cumulative dose of chemotherapy for standard and high-risk Hodgkin lymphoma with no impairment of outcome.
2007-02-01
Gastric distension by ingesting food is useful in the evaluation of primary gastric cancer by FDG PET.
2007-02
Kidney modelling for FDG excretion with PET.
2007
Structural basis for substrate binding and regioselective oxidation of monosaccharides at C3 by pyranose 2-oxidase.
2006-11-17
F-18 fluorodeoxyglucose PET/CT as an imaging tool for staging and restaging cutaneous angiosarcoma of the scalp.
2006-09
Patents
Name Type Language
.ALPHA.-D-GLUCOPYRANOSE, 2-DEOXY-2-FLUORO
Preferred Name English
FLUDEOXYGLUCOSE
USP-RS   VANDF  
Common Name English
FLUDEOXYGLUCOSE [USP-RS]
Common Name English
FLUDEOXYGLUCOSE [VANDF]
Common Name English
D-GLUCOSE, 2-DEOXY-2-FLUORO-
Systematic Name English
Code System Code Type Description
FDA UNII
ZO2JV75L55
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
SMS_ID
100000141745
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
WIKIPEDIA
Fludeoxyglucose
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
RS_ITEM_NUM
1272907
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
EPA CompTox
DTXSID701311592
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
CAS
29702-43-0
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
EVMPD
SUB96345
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY
CAS
62182-10-9
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
ALTERNATIVE
PUBCHEM
170049
Created by admin on Mon Mar 31 17:47:33 GMT 2025 , Edited by admin on Mon Mar 31 17:47:33 GMT 2025
PRIMARY