U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

(±)-2,3A-di-epi-Perindopril is a mixture of two isomers (S, SR, RR) and (R, RS, SS) which are both inactive epimers of the antihypertensive drug perindopril, although the (R, RS, SS) isomer possesses better activity.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


(±)-2',7A-DI-EPI-PERINDOPRIL is a mixture of two isomers (S, SR, RS) and (R, RS, SR) which are both almost inactive epimers in of the antihypertensive drug perindopril.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


(2'R,3AR)-2',3A-di-epi-Perindopril is an epimer (S, RS, RS) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This form of the drug is much less active.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


(±)-1'',7A-di-epi-Perindopril is a mixture of two isomers (S, SR, SR) and (R, RS, RS). The first of which is a less active epimer of the antihypertensive drug perindopril, while the second one is almost completely inactive.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


(±)-1'',2'-di-epi-Perindopril is a mixture of two isomers: (R, RR, SS) and (S, SS, RR) which are both inactive epimers of the antihypertensive drug perindopril.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)



(±)-7A-epi-Perindopril is a mixture of two isomers (S, SR, SS) and (R, RS, RR) each of which is an isomer of the antihypertensive drug perindopril. The first of which has the same activity as the parent compound while the second one is almost inactive.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)



(3AR)-3A-epi-Perindopril is an epimer (S, RS, SS) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This epimer possesses equal activity with the parent compound, perindopril.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


(1''R)-1''-epi-Perindopril is an epimer of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. (1''R)-1''-epe-Perindopril has configuration S, SS, SR and is less active than the parent drug.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)


(±)-2-epi-Perindopril is a mixture of two isomers (R, SS, SS) and (S, RR, RR) which are both inactive epimers of the antihypertensive drug perindopril.