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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2',3A-DI-EPI-PERINDOPRIL, (2'R,3AR)-

SMILES

CCC[C@H](N[C@H](C)C(=O)N1[C@H]2CCCC[C@@H]2C[C@H]1C(O)=O)C(=O)OCC

InChI

InChIKey=IPVQLZZIHOAWMC-OWYFMNJBSA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14+,15+,16+/m1/s1

HIDE SMILES / InChI
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

(2'R,3AR)-2',3A-di-epi-Perindopril is an epimer (S, RS, RS) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This form of the drug is much less active.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:03:04 GMT 2025
Edited
by admin
on Mon Mar 31 23:03:04 GMT 2025
Record UNII
F4ELM88F0Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2',3A-DI-EPI-PERINDOPRIL, (2'R,3AR)-
Common Name English
1H-INDOLE-2-CARBOXYLIC ACID, 1-(2-((1-(ETHOXYCARBONYL)BUTYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S-(1(S*(R*)),2.ALPHA.,3A.ALPHA.,7A.BETA.))-
Preferred Name English
Code System Code Type Description
PUBCHEM
72941694
Created by admin on Mon Mar 31 23:03:04 GMT 2025 , Edited by admin on Mon Mar 31 23:03:04 GMT 2025
PRIMARY
FDA UNII
F4ELM88F0Z
Created by admin on Mon Mar 31 23:03:04 GMT 2025 , Edited by admin on Mon Mar 31 23:03:04 GMT 2025
PRIMARY
CAS
145513-59-3
Created by admin on Mon Mar 31 23:03:04 GMT 2025 , Edited by admin on Mon Mar 31 23:03:04 GMT 2025
PRIMARY
NIH
NCATS
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