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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 7A-EPI-PERINDOPRIL, (7AR)-

SMILES

[H][C@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@]1([H])CCCC2)C(O)=O

InChI

InChIKey=IPVQLZZIHOAWMC-GVRJEKJASA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15+,16-/m0/s1

HIDE SMILES / InChI

Description

(±)-7A-epi-Perindopril is a mixture of two isomers (S, SR, SS) and (R, RS, RR) each of which is an isomer of the antihypertensive drug perindopril. The first of which has the same activity as the parent compound while the second one is almost inactive.

CNS Activity

CNS Non-penetrant
1014

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
dog: 1 mg/kg
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
7A-EPI-PERINDOPRIL, (7AR)-
Common Name English
1H-INDOLE-2-CARBOXYLIC ACID, 1-(2-((1-(ETHOXYCARBONYL)BUTYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S-(1(R*(R*)),2.ALPHA.,3A.BETA.,7A.ALPHA.))-
Systematic Name English
Code System Code Type Description
CAS
145513-30-0
Created by admin on Sat Dec 16 08:30:44 GMT 2023 , Edited by admin on Sat Dec 16 08:30:44 GMT 2023
PRIMARY
FDA UNII
R99KV37CY8
Created by admin on Sat Dec 16 08:30:44 GMT 2023 , Edited by admin on Sat Dec 16 08:30:44 GMT 2023
PRIMARY
PUBCHEM
72941688
Created by admin on Sat Dec 16 08:30:44 GMT 2023 , Edited by admin on Sat Dec 16 08:30:44 GMT 2023
PRIMARY
NIH
NCATS
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