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Restrict the search for
amphotericin b
to a specific field?
Status:
Investigational
Source:
NCT01594723: Phase 2 Interventional Active, not recruiting Neoplasms, Hematologic
(2012)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
An orally bioavailable imidazopyridazine and inhibitor of Janus kinase 2 mutant V617F (JAK2V617F), with potential antineoplastic activity. Upon oral administration, gandotinib selectively and competitively inhibits the activation of JAK2V617F, which may result in the inhibition of the JAK-STAT signaling pathway and the induction of apoptosis in JAK2V617F-expressing tumor cells. Gandotinib is in phase II clinical trials by Lilly for the treatment of myeloproliferative disorders.
Class (Stereo):
CHEMICAL (RACEMIC)
Nitramisole, an imidazothiazole derivative, is an anthelmintic. Nitramisole was effective against migrating Strongylus vulgaris larvae in ponies. Treatment of infected ponies with Nitramisole resulted both a clinical and radical cure.
Status:
Investigational
Source:
INN:racemoramide [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Racemoramide (also known as Moramide) is an opioid analgesic with a central structural action. In clinical trials, Racemoramide shows a strong analgesic action and low toxicity.
Status:
Investigational
Source:
INN:sonrotoclax [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:palazestrant [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
NCT04205227: Phase 1/Phase 2 Interventional Active, not recruiting Cancer
(2020)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:edecesertib [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
NCT01847521: Phase 2 Interventional Completed Autism Spectrum Disorders
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and cancer. Luteolin possesses a variety of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial and anticancer activities. Numerous studies have shown that luteolin possesses beneficial neuroprotective effects both in vitro and in vivo.
Status:
Investigational
Source:
INN:brimarafenib [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
