NITRAMISOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H11N3O2S
Molecular Weight	249.289
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O-][N+](=O)C1=CC=CC(=C1)C2CN3CCSC3=N2

InChI

InChIKey=RFAYUIIWPKWNKY-UHFFFAOYSA-N

InChI=1S/C11H11N3O2S/c15-14(16)9-3-1-2-8(6-9)10-7-13-4-5-17-11(13)12-10/h1-3,6,10H,4-5,7H2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7397601 | https://www.ncbi.nlm.nih.gov/pubmed/7147006

Nitramisole, an imidazothiazole derivative, is an anthelmintic. Nitramisole was effective against migrating Strongylus vulgaris larvae in ponies. Treatment of infected ponies with Nitramisole resulted both a clinical and radical cure.

Approval Year

PubMed

Title	Date	PubMed
Evaluation of pyrantel pamoate, nitramisole and avermectin B1a against migrating Strongylus vulgaris larvae.	1980 Jan	7397601

Patents

Sample Use Guides

In Vivo Use Guide

Ponies were infected, each with 2000 infective Strongylus vulgaris larvae. Nitramisole was administered on day 7 to one group via a stomach tube at the rate of 8 mg/kg.

Route of Administration: Intragastric

Name

Type

Language

NITRAMISOLE

Official Name

English

nitramisole [INN]

Common Name

English

(±)-2,3,5,6-TETRAHYDRO-6-(M-NITROPHENYL)-IMIDAZO(2,1-B)THIAZOLE

Systematic Name

English

IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-(M-NITROPHENYL)-

Systematic Name

English

IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-(3-NITROPHENYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250