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Search results for fludarabine root_notes_note in Note (approximate match)
AMPROTROPINE (Syntropan) is the phosphate salt of
3 diethylamine, 2.2 dimethylpropanol
tropic acid ester. Syntropan is antispasmodic. Its main effect is parasympathetic, and its internal uses are
chiefly the same as those of atropine. Syntropan produces relaxation of the tone of the stomach and inhibition of peristaltic activity. The effect of syntropan on gastric secretion excited by a meat extract meal and histamine is weak as compared with atropine. Its
advantages as a mydriatic were also described: the rapid effect; the short duration; no general dangers nor discomforts; no local dangers, as damaging the corneal epithelium, or increasing the intraocular
pressure; no delay in returning to work for the patient.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
1,2-Dipalmitoyl-sn-glycero-3-phosphate monosodium salt (Phosphatidic Acid, DPPA) is a bioactive phospholipid. Dipalmitoylphosphatidic acid (DPPA) is a minor
phospholipid metabolite that is involved in lipid
biosynthesis. DPPA has two palmitic acid moieties
instead of AA and can convert to lyso-PA to increase
Bcl-2 expression in Hela cells but not in B lymphoma
cells. DPPA significantly inhibited tumor
growth, cell proliferation and tumor angiogenesis.
Furthermore, DPPA strongly arrested the G2/M
transition and further inhibited cell cycle progression
in MDA-MB-231 cells. cyclin B1 (CCNB1) was the DPPA target that
regulated cellular proliferation in human TNBC. DPPA, as an anti-cancer drug, inhibited the expression of CCNB1 to arrest the G2/M transition in human TNBC.