U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

Showing 41 - 50 of 142 results

Status:
US Previously Marketed
Source:
21 CFR 310.544(a) smoking deterrent quinine ascorbate
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Quinine ascorbate is a salt of antimalarial drug quinine and ascorbic acid (vitamin C). Ascorbate reduces the potency of quinolone-containing anti-malarial drugs. Quinine ascorbate was marketed as a component of over-the-counter smoking deterrent products but was not recognized as safe by the FDA regulation in 1993.
Status:
US Previously Marketed
Source:
21 CFR 310.531(a) boil treatment isobutamben
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Isobutamben is a local anaesthetic agent, used for surgery and dental procedures. The drug was marketed under the name Cycloform, however its current marketing status is unknown and supposed to be "withdrawn".
Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(27)(viii) antimicrobial:personnel hand wash tribromsalan
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Tribromsalan (trade name Temasept IV) is a member of brominated salicylanilides chemical family. Was initially registered in 1964 manufactured by Hexcel Corporation, Sherwin Williams Chemicals. It is a pesticide type with antimicrobial and preservative features found its application in hard surfaces, laundry, textiles, and manufactured products. Types of tribromsalan formulations include solid, solutions, and sprays and its usual carrier is soap. Limited exposure is possible based on the registered uses of these products as disinfectants, laundry additives, textile preservatives, and manufactured products and do not include direct application to a food or feed crop. In 1974 FDA directed the removal of tribromsalan drug products from the market because it was found to make skin extrasensitive to light. For the same reason it was forbidden in Europe since the 1970s. Since 1982 the OTC topical antimicrobial drug products rulemaking was reopened and included tribromsalan in a list of antimicrobial OTC Drug Products. At present tribromsalan is considered an antiseptic active ingredient eligible for the OTC use as a consumer antiseptic hand and body wash drug product. It was reported that tribromsalan, inhibits NF-kappaB signaling via inhibition of IkappaBalpha phosphorylation with IC50 of 7.9 uM. This finding provides new information on activities and mechanisms of action that may suggest mechanisms of potential novel applications in cancer treatment of such drugs as tribromsalan.
Status:
US Previously Marketed
Source:
21 CFR 310.502(a) certain drugs dibromsalan
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dibromsalan (4',5-dibromosalicylanilide) is a disinfectant. Dibromsalan is a halogenated phenol derivative chemically related to bithionol and tetrachlorosalicylanilide (TCSA). It has antimicrobial properties. It was an ingredient of some commercial soaps. It was withdrawn from the market for reasons of safety. Dibromsalan was shown to cause photodermatitis.
Status:
Possibly Marketed Outside US
Source:
NCT03692286: Phase 4 Interventional Completed Postoperative Pain
(2019)
Source URL:
First approved in 2008
Source:
Acne Care Swab Step 1 Clean by Swabplus Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Silver is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. According to FDA final rule, all over-the-counter drug products containing colloidal silver ingredients or silver salts for internal or external use are not generally recognized as safe and effective and are misbranded.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.548
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Silver benzoate is a water soluble crystalline salt composed of silver and benzoic acid with the formula C7H5AgO2 with marked antimicrobial activity. Silver benzoate can be used in synthesis of silver nanoparticle, and in the synthesis of triphenyltinbenzoate. Silver benzoate along with 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD) is an efficient catalytic system for the reaction of carbon dioxide with various ketones.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.548
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Silver oxalate is a chemical compound of silver. It is used in experimental petrology to add carbon dioxide to experiments. Silver is a metallic element with the chemical symbol Ag and atomic number 47. It occurs naturally in its pure, free form, as an alloy with gold and other metals, and in minerals such as argentite and chlorargyrite. Silver oxalate, one of the coordination polymer crystals, is a promising synthetic precursor for transformation into Ag nanoparticles without any reducing chemicals via thermal decomposition of the oxalate ions.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.547
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.546
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Quinine iodosulfate (herapathite) is a mixed salt of quinine and iodine. Its crystals are dichroic - they function as excellent linear light polarizers absorbing virtually all the light polarized along the shorter axis of the best-developed face. A sheet of quinine iodosulfate sandwiched between two glass plates is called polaroid. Polaroids find applications in areas such as automobile headlights and windscreens, hotel and aircraft windows and sunglasses.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.548
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Silver phosphate or silver orthophosphate is a chemical compound consists of silver and phosphate. Silver phosphate has different applications, in photocatalysis to remove the antibiotic from water, in silver staining of biological materials, in photography.