U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 401 - 410 of 1728 results

Status:
Investigational
Source:
INN:chaulmosulfone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Chaulmosulfone is cyclopentanetridecananilide derivative with potent antifungal activity.
Status:
Investigational
Source:
INN:nifurvidine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nifurvidine, a 5-nitrofuran derivative, is an antibacterial agent. It was used for controlling Salmonella choleraesuis in swine. The mode of action of 5-nitrofuran analogues is based on red-ox biotransformation.
Status:
Investigational
Source:
Bol Chil Parasitol. 1983;38(3-4):42-9.: Not Applicable Veterinary clinical trial Completed Sheep Diseases
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Niclofolan (bayer 9015, Bilevon) is a biphenyl anthelmintic compound. Niclofolan is used orally towards the treatment of Fasciola hepatica infection. Niclofolan therapy achieved elimination of eggs from the feces and normalization of eosinophil counts, liver enzymes and Fasciola titers, suggesting eradication of biliary flukes. Niclofolan has also been used in the treatment of Paragonimus westermani in dogs and cats and P. iloktsuenensis in rats. It was proved that administration of daily dose of 1.0 mg/kg body weight for 3 days or in 2 doses of 2.0 mg/kg body weight by alternate days were evidently effective for the infected dogs, cats and rats with the lung flukes, and toxic manifestations were not found.
Status:
Investigational
Source:
INN:tameticillin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Tamethicillin is a basic ester pro-drug of methicillin (MET) which is converted in the body by non-specific esterases to MET. Tamethicillin was used as an antibacterial agent in the veterinary as a useful alternative for the treatment of mastitis in livestock, especially in mastitis due to beta-lactamase-producing Staphylococcus.
Status:
Investigational
Source:
INN:oxetacillin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Oxetacillin was developed as an antibacterial drug that has never been marketed.
Status:
Investigational
Source:
INN:pexantel
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Pexantel is an anthelmintic, which was used to treat filariasis.
Status:
Investigational
Source:
INN:etibendazole
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:

Etibendazole (R34803 or methyl [5-(2-(4-fluorophenyl)-1,3-dioxolan-2-yl)-1H-benzimidazole-2-yl] carbamate), a benzimidazole derivative, is a microtubule inhibitor. Etibendazole exerts antihelmintic activity.
Status:
Investigational
Source:
INN:forminitrazole [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Forminitrazole was studied as an antiprotozoal and antitrichomonal agent. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:fenbenicillin
Source URL:

Class (Stereo):
CHEMICAL (EPIMERIC)

Fenbenicillin (phenoxybenzylpenicillin) is an acid-stable, orally active penicillin. Fenbenicillin demonstrated antibacterial activity in patients suffering from streptococcal, pneumococcal, and penicillin-sensitive staphylococcal infections.
Status:
Investigational
Source:
INN:irloxacin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

IRLOXACIN, a fluorinated quinolone derivative, is an antibacterial agent with proved activity against both gram-positive and gram-negative bacteria.