FENBENICILLIN

Details

Stereochemistry	EPIMERIC
Molecular Formula	C22H22N2O5S
Molecular Weight	426.485
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(OC3=CC=CC=C3)C4=CC=CC=C4)C(O)=O

InChI

InChIKey=VZPPEUOYDWPUKO-MQWDNKACSA-N

InChI=1S/C22H22N2O5S/c1-22(2)17(21(27)28)24-19(26)15(20(24)30-22)23-18(25)16(13-9-5-3-6-10-13)29-14-11-7-4-8-12-14/h3-12,15-17,20H,1-2H3,(H,23,25)(H,27,28)/t15-,16?,17+,20-/m1/s1

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14493506 | https://www.ncbi.nlm.nih.gov/pubmed/13876963

Fenbenicillin (phenoxybenzylpenicillin) is an acid-stable, orally active penicillin. Fenbenicillin demonstrated antibacterial activity in patients suffering from streptococcal, pneumococcal, and penicillin-sensitive staphylococcal infections.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Phenoxybenzylpenicillin].	1962 Apr 30	13875616
Bacteriological and pharmacological properties of phenoxybenzylpenicillin.	1962 Jan 13	14493506
Bacteriological and clinical studies with phenoxybenzylpenicillin.	1962 Jan 13	13876963
Phenoxybenzylpenicillin in general practice.	1963 Jun	13992306
[PHENOXYBENZYLPENICILLIN (PHENBENICILLIN) AND ITS MICROBIOLOGICAL STUDY].	1964 Jan	14191800

Sample Use Guides

In Vivo Use Guide

125 mg six-hourly

Route of Administration: Oral

Name

Type

Language

FENBENICILLIN

Official Name

English

FENBENICILLIN [MI]

Common Name

English

(ALPHA-PHENOXYBENZYL)PENICILLIN

Common Name

English

fenbenicillin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1500