U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 391 - 400 of 412 results

Status:
US Previously Marketed
Source:
Veralba by Pitman-Moore (Dow Chem., USA)
(1953)
Source URL:
First approved in 1953
Source:
Veralba by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Protoveratrine B is one of two alkaloids isolated from the plant Veratrum albumen. The main effect of both alkaloids is vasodilation in all vascular beds thereby reducing blood pressure. In the 1950's it was recognized that Protoveratrine B is the preferred compound which can be administered at significantly higher doses before the patient begins to vomit.
Status:
US Previously Marketed
Source:
Provell Maleate by Lilly
(1953)
Source URL:
First approved in 1953
Source:
Provell Maleate by Lilly
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Protoveratrine A, the principal alkaloid of Veratrum album, has been used in the treatment of hypertension but has largely been replaced by drugs with fewer adverse effects.
Status:
US Previously Marketed
Source:
Veralba by Pitman-Moore (Dow Chem., USA)
(1953)
Source URL:
First approved in 1953
Source:
Veralba by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Protoveratrine B is one of two alkaloids isolated from the plant Veratrum albumen. The main effect of both alkaloids is vasodilation in all vascular beds thereby reducing blood pressure. In the 1950's it was recognized that Protoveratrine B is the preferred compound which can be administered at significantly higher doses before the patient begins to vomit.
Status:
US Previously Marketed
Source:
Provell Maleate by Lilly
(1953)
Source URL:
First approved in 1953
Source:
Provell Maleate by Lilly
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Protoveratrine A, the principal alkaloid of Veratrum album, has been used in the treatment of hypertension but has largely been replaced by drugs with fewer adverse effects.
Status:
US Previously Marketed
First approved in 1947
Source:
Synestrol by White (Schering)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of the vulva. Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis). Dienestrol currently discontinued in US, but still in market in some other counties
Status:
US Previously Marketed
First approved in 1947
Source:
Synestrol by White (Schering)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of the vulva. Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis). Dienestrol currently discontinued in US, but still in market in some other counties
Status:
US Previously Marketed
Source:
Solution of Lead Subacetate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Solution of Lead Subacetate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Lead(II) acetate is a white crystalline chemical compound with a sweetish taste. Lead(II) acetate is used as a mordant in textile printing and dyeing, as a drier in paints and varnishes, and in preparing other lead compounds. It was historically used as a sweetener and for cosmetics.
Status:
Possibly Marketed Outside US
Source:
bdr Re-lax 3 multiple level serum highly-potential youth by Hanaim International Llc
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
First approved in 2015

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
First approved in 2011

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Prezatide is a tripeptide molecule consisiting of lysine, glycine and histidine, also known as GHK (glycyl-L-histidyl-L-lysine), that forms a complex with copper ions. Prezatide is used in cosmetic products (skin and hair) and is known help wound healing. Prezatide increases the synthesis and deposition of type I collagen and glycosaminoglycan. It is thought to play a role in the modulation of tissue remodeling by increases the expression of matrix metalloproteinase-2, as well as tissue inhibitor of matrix metalloproteinases-1 and -2. Prezatide has antioxidant activity due to its ability to supply copper for superoxide dismutase and anti-inflammatory ability due to the blockage the of iron (Fe2+) release during injury.

Showing 391 - 400 of 412 results