U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 38031 - 38040 of 39591 results

Status:
US Previously Marketed
Source:
Sodium Hypophosphite U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Hypophosphite U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Hypophosphite is a strong reducing agent, that has been used in the 1850s as a remedy for pulmonary tuberculosis. Hypophosphites were used extensively in pharmaceutical preparations, elixirs, and tonics. Hypophosphite does not appear to have adverse toxicological effects, and the sodium, calcium, and potassium salts are considered GRAS. Hypophosphite use in foods may not be limited to one function. Hypophosphites have been used in foods as antioxidants, stabilizers, meat pickling accelerator, and vegetable protein flow inducer.
Status:
US Previously Marketed
Source:
Sodium Borate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Borate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

BORATE, a salt of boric acid, is used as a food additive in the European Union. This additive is authorized for use as preservatives of sturgeon eggs (caviar).
Gallic acid is a polyphenol found in a variety of foods and herbs. Several studies have shown thta gallic acid has neuroprotective and anti-oxidant properties and can be a promising candidate for the treatment of cancer, cardiovascular diseases, neurodegenerative disorders, fatty liver disease and many others. Gallic acid acts by protecting cells against oxidative damage caused by reactive species often encountered in biological systems including, hydroxyl, superoxide and peroxyl and the non-radicals, hydrogen peroxide and hypochlorous acid. However, its ability to induce apoptosis, is mainly associated with its prooxidant, rather than antioxidant behavior.
Status:
US Previously Marketed
Source:
LENIC WITH NIACIN LINOLEIC ACID by CROOKES-BARNES
(1961)
Source URL:
First marketed in 1921
Source:
linoleic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Linoleic acid is a naturally occurring omega-6 essential fatty acid, present in a variety of foods, including the oils. Linoleic acid is a precursor for arachidonic acid biosynthesis; on the first enzymatic step of the pathway involves delta-6-desaturase, which converts linoleic acid to gamma-lenolenic acid. Linoleic acid has beneficial effects on human skin and hair. Replacement of saturated fat with linoleic acid is advocated to improve serum lipoprotein profiles and reduce the risk of coronary artery disease. Linoleic acid was tested in clinical trilas as a possible remedy against multiple sclerosis.
Status:
US Previously Marketed
Source:
1,2-ethanedisulfonic acid
(1921)
Source URL:
First marketed in 1921
Source:
1,2-ethanedisulfonic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Sodium 1,2-ethanedisulfonate dihydrate is salt of ethanedisulfonic acid. Ethanedisulfonic acid is used in pharmaceutical formulations of some antipsychotic compounds to form salts with the active ingredients, known as edisylates.
Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.
Glycyrrhizic Acid is specific compound isolated from licorice plants. Ammonium Glycyrrhizate (also known as GLYCYRRHIZIN, AMMONIATED) is a salt, was investigated to be a safe and is used as ingredient in the formulation of makeup, fragrance, hair care, skin care, shaving, personal hygiene and suntan products.
Status:
US Previously Marketed
Source:
1,2-ethanedisulfonic acid
(1921)
Source URL:
First marketed in 1921
Source:
1,2-ethanedisulfonic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Sodium 1,2-ethanedisulfonate dihydrate is salt of ethanedisulfonic acid. Ethanedisulfonic acid is used in pharmaceutical formulations of some antipsychotic compounds to form salts with the active ingredients, known as edisylates.
Status:
US Previously Marketed
Source:
Sparteine Sulphate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sparteine Sulphate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalents calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent. It is also used as a chiral base in organic chemistry, and as a ligand in organic chemical synthesis. Marketed under the brand name Spal in Taiwan and Sparteine in Brazil.
Glycyrrhizic Acid is specific compound isolated from licorice plants. Ammonium Glycyrrhizate (also known as GLYCYRRHIZIN, AMMONIATED) is a salt, was investigated to be a safe and is used as ingredient in the formulation of makeup, fragrance, hair care, skin care, shaving, personal hygiene and suntan products.

Showing 38031 - 38040 of 39591 results