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Search results for deoxycholic root_names_stdName in Standardized Name (approximate match)
Status:
Possibly Marketed Outside US
First approved in 2017
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinnamic acid is a polyphenol found in cinnamon oil and used in commercial flavorings. Recent studies have shown the pharmacological properties of cinnamic acid and its derivatives, including hepatoprotective, anti-oxidant, and anti-diabetic activities. In preclinical studies cinnamic acid demonstrated to be a promising candidate for the treatment ob obesity and diabetes. The mechanism of action of cinnamic acid in obesity is explained by its ability to inhibit lipases and ACE (angiotensin-converting enzyme). However, there are several hypotesis regarding the effect of cinnamic acid in diabetes: cinnamic acid enhances glucose-induced insulin secretion, prevents palmitic acid-induced lipotoxicity, inhibits palmitic acid-induced alteration of lipogenic gene and protein expression (AMPK, SREBP-1c, FAS, ACC), inhibits DPP IV, exhibits an additive effect on the uptake of glucose, stimulates adiponectin secretion, etc.
Status:
Possibly Marketed Outside US
Source:
505G(a)(3)
(2017)
Source URL:
First approved in 2017
Source:
505G(a)(3)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
First approved in 2017
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Trimethylamine (or TMA) a tertiary amine, is synthesized by the action of microbial enzymes in humans. The decrease of TMA metabolism and excessive TMA excretion cause the disease trimethylaminuria and some other diseases associated with the abnormal level of TMA, e.g., obesity, diabetes, cardiovascular diseases. It was shown, that TMS is a full agonist of human trace amine-associated receptor 5, TAAR5. In addition, TMA is a precursor of N-oxide form, an emergent biomarker of human health that can lead to renal diseases, neurological disorders, and cancer.
Status:
Possibly Marketed Outside US
Source:
XR CELLULAR MAGIC by MESO SYSTEM S.A.
(2016)
Source URL:
First approved in 2016
Source:
XR CELLULAR MAGIC by MESO SYSTEM S.A.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
DR. COLOR EFFECT RED by ES PURE VINE INC.
(2016)
Source URL:
First approved in 2016
Source:
DR. COLOR EFFECT RED by ES PURE VINE INC.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2016)
Source URL:
First approved in 2016
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
D,L-Glutamic acid is a mixture of naturally occurring proteinogenic L-glutamic acid and non-proteinogenic D-glutamic acid. D,L-Glutamic acid is used to study mechanisms of crystal formation and self-assembly on surfaces and copolymer development. D-Glutamic acid is a component of bacterial peptidoglycans, produced by glutamate racemase.
Status:
Possibly Marketed Outside US
First approved in 2016
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Uric acid, generated from the metabolism of purines, has proven and emerging roles in human disease. Humans produce large quantities of uric acid. Excess serum accumulation of uric acid can lead to a type of arthritis known as gout. Hyperuricemia may increase risk factors for cardiovascular disease. High serum uric acid was associated with higher risk of type 2 diabetes and other diseases.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2016)
Source URL:
First approved in 2016
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
D,L-Glutamic acid is a mixture of naturally occurring proteinogenic L-glutamic acid and non-proteinogenic D-glutamic acid. D,L-Glutamic acid is used to study mechanisms of crystal formation and self-assembly on surfaces and copolymer development. D-Glutamic acid is a component of bacterial peptidoglycans, produced by glutamate racemase.
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2016)
Source URL:
First approved in 2016
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
First approved in 2016
Source:
21 CFR 356
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Disodiurn salt of Arsonoacetic acid has been used in veterinary to treat anaplasmosis (babesiasis); as general stimulant in nervous disease; for eclampsia of bitches, and with adjuncts in chronic eczema and follicular mange. Arsonoacetic acid has not featured much in human medicine, a Chinese patent however, was filed in 2003 for arsonoacetic acid and its methyl or ethyl derivatives as chemotherapeutic drugs again liver cancer.
