Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H9N.ClH |
| Molecular Weight | 95.571 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(C)C
InChI
InChIKey=SZYJELPVAFJOGJ-UHFFFAOYSA-N
InChI=1S/C3H9N.ClH/c1-4(2)3;/h1-3H3;1H
| Molecular Formula | C3H9N |
| Molecular Weight | 59.1103 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Trimethylamine (or TMA) a tertiary amine, is synthesized by the action of microbial enzymes in humans. The decrease of TMA metabolism and excessive TMA excretion cause the disease trimethylaminuria and some other diseases associated with the abnormal level of TMA, e.g., obesity, diabetes, cardiovascular diseases. It was shown, that TMS is a full agonist of human trace amine-associated receptor 5, TAAR5. In addition, TMA is a precursor of N-oxide form, an emergent biomarker of human health that can lead to renal diseases, neurological disorders, and cancer.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Sequencing, expression, and characterization of cDNA expressed flavin-containing monooxygenase 2 from mouse. | 2001 |
|
| Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling. | 2001 |
|
| Identification of a twin-arginine leader-binding protein. | 2001 Apr |
|
| Trimethylamine and total volatile basic nitrogen determination by flow injection/gas diffusion in Mediterranean hake (Merluccius merluccius). | 2001 Apr |
|
| Syntheses of the first amine-dicarboxyboranes and their bis(methylester) and bis(N-ethylamide) derivatives. | 2001 Apr 9 |
|
| Coupled electron/proton transfer in complex flavoproteins: solvent kinetic isotope effect studies of electron transfer in xanthine oxidase and trimethylamine dehydrogenase. | 2001 Aug 17 |
|
| A genetic screen for suppressors of Escherichia coli Tat signal peptide mutations establishes a critical role for the second arginine within the twin-arginine motif. | 2001 Dec |
|
| Population distribution of human flavin-containing monooxygenase form 3: gene polymorphisms. | 2001 Dec |
|
| Efficient synthesis of the cholinephosphate phospholipid headgroup. | 2001 Feb |
|
| In vivo variability of TMA oxidation is partially mediated by polymorphisms of the FMO3 gene. | 2001 Jul |
|
| Cloning, sequencing, tissue distribution, and heterologous expression of rat flavin-containing monooxygenase 3. | 2001 Jul 1 |
|
| Inactivation of C30A trimethylamine dehydrogenase by N-cyclopropyl-alpha-methylbenzylamine, 1-phenylcyclopropylamine, and phenylhydrazine. | 2001 Jul 24 |
|
| pH regulation and buffering power in gastric smooth muscle. | 2001 Jun |
|
| Detection of the mutated K-Ras biomarker in colorectal carcinoma. | 2001 Jun |
|
| Characterization of Methanococcus voltaei strain P2F9701a: a new methanogen isolated from estuarine environment. | 2001 Jun |
|
| Investigation of Escherichia coli dimethyl sulfoxide reductase assembly and processing in strains defective for the sec-independent protein translocation system membrane targeting and translocation. | 2001 Jun 8 |
|
| Olfactory response to mushroom composting emissions as a function of chemical concentration. | 2001 May-Jun |
|
| Silicon surfaces as electron acceptors: dative bonding of amines with Si(001) and Si(111) surfaces. | 2001 Nov 7 |
|
| alpha,beta-poly(asparthylhydrazide)-glycidyltrimethylammonium chloride copolymers (PAHy-GTA): novel polymers with potential for DNA delivery. | 2001 Nov 9 |
|
| Pharmacokinetics of trimethylamine in rats, including the effects of a synthetic diet. | 2001 Oct |
|
| A computational study of the reactions of thiiranes with ammonia and amines. | 2001 Sep 7 |
|
| Protein dynamics enhance electronic coupling in electron transfer complexes. | 2001 Sep 7 |
|
| Validation of methyl malondialdehyde as internal standard for malondialdehyde detection by capillary electrophoresis. | 2002 Aug 1 |
|
| Chitosan as an edible invisible film for quality preservation of herring and atlantic cod. | 2002 Aug 28 |
|
| Monomeric sarcosine oxidase: evidence for an ionizable group in the E.S complex. | 2002 Aug 6 |
|
| Trimethylamine oxide accumulation in marine animals: relationship to acylglycerol storage. | 2002 Feb |
|
| High-performance liquid chromatographic determination of alpha-amino acids in pharmaceutical dosage forms using aqueous mobile phase containing copper (II) ions. | 2002 Jan-Feb |
|
| Amino acid decarboxylase activity and other chemical characteristics as related to freshness loss in iced cod (Gadus morhua). | 2002 Jul |
|
| Volatile N-nitrosamine inhibition after intake Korean green tea and Maesil (Prunus mume SIEB. et ZACC.) extracts with an amine-rich diet in subjects ingesting nitrate. | 2002 Jul |
|
| Computational studies of aliphatic amine basicity. | 2002 Jul 26 |
|
| Monovalent cation permeability and Ca(2+) block of the store-operated Ca(2+) current I(CRAC )in rat basophilic leukemia cells. | 2002 Mar |
|
| Gas-phase analysis of trimethylamine, propionic and butyric acids, and sulfur compounds using solid-phase microextraction. | 2002 Mar 1 |
|
| Analysis of spontaneous mRNA cytokine production in peripheral blood. | 2002 Mar 1 |
|
| Sensory, chemical and bacteriological changes in vacuum-packed pressurised squid mantle (Todaropsis eblanae) stored at 4 degrees C. | 2002 Mar 25 |
|
| The effect of intensity and duration on the light-induced sodium and potassium currents in the Hermissenda type B photoreceptor. | 2002 May 15 |
|
| CaiT of Escherichia coli, a new transporter catalyzing L-carnitine/gamma -butyrobetaine exchange. | 2002 Oct 18 |
|
| Characterization and multiple molecular forms of TorD from Shewanella massilia, the putative chaperone of the molybdoenzyme TorA. | 2002 Sep |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:08:25 GMT 2023
by
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on
Fri Dec 15 15:08:25 GMT 2023
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| Record UNII |
UW38SRM77K
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| Record Status |
Validated (UNII)
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PARENT -> SALT/SOLVATE |
