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Showing 21 - 30 of 2,062 results

Status:
US Approved Rx (2010)
First approved in 2001

Class (Stereo):
CHEMICAL (ABSOLUTE)



Bimatoprost (marketed in the US, Canada and Europe by Allergan, under the trade name Lumigan) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is...
Status:
US Approved Rx (2007)
First approved in 1998

Class (Stereo):
CHEMICAL (ACHIRAL)



Risedronic acid is a pyridinyl bisphosphonate that inhibits osteoclast-mediated bone resorption and modulates bone metabolism. The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral m...
Status:
US Approved Rx (2012)
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)



Clopidogrel, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to inhibit blood clots in a variety of conditions such as peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Clopido...
Status:
US Approved Rx (2000)
First approved in 1997

Class (Stereo):
CHEMICAL (ACHIRAL)



Tazarotene is a prodrug and a member of the acetylenic class of retinoids. Following topical application, tazarotene undergoes esterase hydrolysis to form its active metabolite, tazarotenic acid. When treating acne tazarotene may be taken in conjunct...
Status:
US Approved Rx (2013)
First approved in 1996

Class (Stereo):
CHEMICAL (ABSOLUTE)



There is no information in the literature about pharmacological and biological application of definite isomer of valsatran, R – form (also known as VALSARTAN, D- or CGP-49309). However there were found, that in the tablets of valsartan, which are use...
Status:
US Approved Rx (2008)
First approved in 1996

Class (Stereo):
CHEMICAL (ABSOLUTE)



Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. Irinotecan is sold under the brand name Camptosar among others. CAMPTOSAR is a topoisomerase inhibitor indicated for: • First-line therapy in comb...
Status:
US Approved Rx (2010)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Losartan is a selective, competitive angiotensin II receptor type 1 (AT1) antagonist. Losartant is recommended as one of several preferred agents for the initial management of hypertension. Administration of losartan reduces the risk of stroke in pat...
Status:
US Approved Rx (2024)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against ant...
Status:
US Approved Rx (2016)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Aminolevulinic Acid is the first compound in the porphyrin synthesis pathway. The metabolism of aminolevulinic acid (ALA) is the first step in the biochemical pathway resulting in heme synthesis. Aminolevulinic acid is not a photosensitizer, but rat...
Status:
US Approved Rx (2023)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Alendronic acid is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. It is marketed alone as well as in combination with vitamin D. Alendronate inhibits osteoclast-mediated bone-resorption. Like al...