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Search results for telotristat root_codes_WIKIPEDIA in WIKIPEDIA (approximate match)
Status:
Other
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
N-Ethyl-3-piperidyl benzilate (JB-318) is an anticholinergic drug. It is a potent hallucinogenic agent. JB-318 is a psychotomimetic, it has an antitremor action in patients with Parkinson disease.
Ethyl propionate causes topical dissolution of cholesterol gallbladder. It was tested on an animal model of gallstones in 1997, however, there is no information about its further development.
Ethyl thiocyanate was tested as a fumigant in 1951.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Ethyl protocatechuate (ethyl 3,4-dihydroxybenzoate) is a lipophilic compound that acts as a pharmacological hypoxic mimetic and prolyl hydroxylase inhibitor. It might serves as a potential anti-fibrotic agent - the synthesis of 4-hydroxyproline in scleroderma cell cultures was reduced by ethyl 3,4-dihydroxybenzoate. Pharmacological activation of the PHD/HIF-1 alpha pathway by a cell-permeable ethyl-3,4 dihydroxybenzoate prevents mitochondrial dysfunction after warm ischemia-reperfusion in vivo. ethyl 3,4-dihydroxybenzoate might prove useful clinically to decrease or eliminate IR injury associated with liver surgery and transplantation. Ethyl protocatechuate supplementation effectively scaled down hypobaric hypoxia induced cerebral edema with concomitant downregulation of brain NF-κB expression – it might serves as effective hypoxic preconditioning agent in ameliorating hypobaric hypoxia mediated injury in brain.