ETHYL CYANOACETATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H7NO2
Molecular Weight	113.1146
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)CC#N

InChI

InChIKey=ZIUSEGSNTOUIPT-UHFFFAOYSA-N

InChI=1S/C5H7NO2/c1-2-8-5(7)3-4-6/h2-3H2,1H3

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Synthesis and antibacterial activity of fused 1, 2, 4-triazolo[4, 3-a]quinoxaline and oxopyrimido[2', 1':5, 1]-1, 2, 4-triazolo[4, 3-a]quinoxaline derivatives.	2002 Aug	12397623
Palladium-catalyzed arylation of malonates and cyanoesters using sterically hindered trialkyl- and ferrocenyldialkylphosphine ligands.	2002 Jan 25	11798329
Synthesis of ethyl alpha-cyanocinnamates catalyzed by KF-Al2O3 under ultrasound irradiation.	2002 Jul	12154690
A one-pot microwave-assisted synthesis of pyrido[2,3-d]pyrimidines.	2003	14870844
Synthesis and properties of new substituted 1,2,4-triazoles: potential antitumor agents.	2003 Apr 17	12659756
Reaction of [60]fullerene with free radicals generated from active methylene compounds by manganese(III) acetate dihydrate.	2003 Dec 21	14685313
Knoevenagel condensation reaction in a membrane microreactor.	2003 Jan 21	12585399
Synthesis of some new thiazole derivatives of pharmaceutical interest.	2003 Nov	14971309
Electrophilicity parameters for benzylidenemalononitriles.	2003 Sep 5	12946126
Solvent-free reactions of C60 with active methylene compounds, either with or without carbon tetrabromide, in the presence of bases under high-speed vibration milling conditions.	2004 Jun 21	15188036
Direct organocatalytic and highly enantio- and diastereoselective Mannich reactions of alpha-substituted alpha-cyanoacetates.	2005 May 6	15827948
Synthesis and antiviral activity of novel chiral cyanoacrylate derivatives.	2005 Oct 5	16190646
Lanthanide(III) and Yttrium(III) Complexes of Benzimidazole-2-Acetic Acid: Synthesis, Characterisation and Effect of La(III) Complex on Germination of Wheat.	2006	17497017
Synthesis of multisubstituted quinolines from Baylis-Hillman adducts obtained from substituted 2-chloronicotinaldehydes and their antimicrobial activity.	2006 Jul 1	16510289
Synthesis and molluscicidal activity of some 1,3,4-triaryl-5-chloropyrazole, pyrano[2,3-c]pyrazole, pyrazolylphthalazine and pyrano[2,3-d]thiazole derivatives.	2006 Jun	16649159
Ethyl (E)-3-anilino-2-cyano-3-mercaptoacrylate.	2007 Dec 6	21200951
Diethyl 5,5'-thio-bis[2-amino-4-(4-fluoro-phen-yl)-1-phenyl-1H-pyrrole-3-carboxyl-ate].	2007 Dec 6	21200775
Ethyl 3'-cyano-1'-methyl-2-oxo-4'-phenylspiro-[acenaphthene-1,2'-pyrrolidine]-3'-carboxyl-ate.	2008 Jan 16	21201467
Ethyl 5-acetyl-2-amino-4-methyl-thio-phene-3-carboxyl-ate.	2008 May 17	21202599
Ethyl 5-amino-3-methyl-sulfan-yl-1H-pyrazole-4-carboxyl-ate.	2008 Nov 8	21581260
Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties.	2008 Sep	18241958
4-(4-Bromo-phen-yl)-4,5,6,7-tetra-hydro-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile ethanol solvate.	2008 Sep 13	21201133
6,7-Dihydro-4-(4-methoxy-phen-yl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile.	2008 Sep 6	21201100
Antiviral and antischistosomal evaluation of newly synthesized thioglycosides and their acyclic analogues.	2009 Jul-Aug	19791497
A novel and efficient one step synthesis of 2-amino-5-cyano-6-hydroxy-4-aryl pyrimidines and their anti-bacterial activity.	2009 Jun	19036478
Ethyl 3-amino-1-phenyl-1H-benzo[f]chromene-2-carboxyl-ate.	2009 Mar 14	21582501
New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage.	2009 Nov	19616348
Hydroxyapatite supported caesium carbonate as a new recyclable solid base catalyst for the Knoevenagel condensation in water.	2009 Nov 20	20300501
(E)-Ethyl 3-(3-bromo-phen-yl)-2-cyano-acrylate.	2009 Oct 3	21578251
(E)-Ethyl 2-cyano-3-(3,4-dihydr-oxy-5-nitro-phen-yl)acrylate.	2009 Sep 5	21577820
L-Histidine and L-arginine promote Knoevenagel reaction in water.	2010 Aug	20221649
Ethyl 2-amino-6-benzyl-4,5,6,7-tetra-hydro-thieno[2,3-c]pyridine-3-carboxyl-ate.	2010 Dec 24	21522725
Ultrasound-assisted one-pot, three-component synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones.	2010 Jan	19589715
Ethyl 2-amino-7,7-dimethyl-2',5-dioxo-spiro-[5,6,7,8-tetra-hydro-4H-chromene-4,3'(2'H)-1H-indole]-3-carboxyl-ate.	2010 Jan 9	21579735
One-pot synthesis of 4,6-diaryl-2-oxo(imino)-1,2-dihydropyridine-3-carbonitrile; a New Scaffold for p38alpha MAP kinase inhibition.	2010 Jul 12	20518551
Mono(NCN-pincer palladium)-metalloporphyrin catalysts: evidence for supramolecular bimetallic catalysis.	2010 Jul 21	20520882
Novel 6,8-dibromo-4(3H)-quinazolinone derivatives of promising anti-inflammatory and analgesic properties.	2010 Mar-Apr	20369793
A convenient one-pot synthesis of 3-amino-2, 5-dihydropyridazine and pyrimidine derivatives in the presence of high surface area MgO as a highly effective heterogeneous base catalyst.	2010 May	19543800
A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulation of a pyrimidine derivative.	2010 Nov 9	21085498
Green one pot solvent-free synthesis of pyrano[2,3-c]-pyrazoles and pyrazolo[1,5-a]pyrimidines.	2010 Sep 20	20877248
(E)-Ethyl 2-cyano-3-[5-nitro-2-(pyrrolidin-1-yl)phen-yl]acrylate.	2010 Sep 4	21587494

Patents

Name

Type

Language

ETHYL CYANOACETATE

Systematic Name

English

CYANOACETIC ESTER

Common Name

English

ETHYL CYANOACETATE [HSDB]

Common Name

English

ETHYL CYANOETHANOATE

Systematic Name

English

ETHYL CYANOACETATE [MI]

Common Name

English

ACID ETHYL ESTER NITRILE

Common Name

English

2-CYANOACETIC ACID ETHYL ESTER

Systematic Name

English

NSC-8844

Code

English

Code System Code Type Description

CAS

105-56-6