U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 21 - 22 of 22 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

3-Methylxanthine is a metabolite of caffeine and theophylline.
Status:
US Previously Marketed
Source:
Theobromine Sodio-Salicylate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Theobromine Sodio-Salicylate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Theobromine is the primary alkaloid present in the cocoa and chocolate. Theobromine is found in the shells and beans of the cacao plant and it is extracted from the husks of the bean and used for the synthesis of caffeine. Theobromine is an adenosine A1 and A2a receptor antagonist. Thesodate is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. The symptomatic adverse reactions produced by theobromine are more or less tolerable and if they become severe, they can be treated symptomatically, these include anxiety, restlessness, tremors, sleeplessness, nausea and vomiting, loss of appetite. Theobromine is currently not in use as a medicinal drug.