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Restrict the search for
methyl salicylate
to a specific field?
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Tropanserin (MDL 72422) is a potent and selective 5-HT3 receptor antagonist. It was investigated as a drug for the treatment of migraine. MDL 72222 was shown to be an effective antimigraine agent in a double-blind
placebo-controlled study.
Status:
Investigational
Source:
NCT02107196: Phase 3 Interventional Completed Irritable Bowel Syndrome With Diarrhea
(2014)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Menarini was developing ibodutant (also known as MEN15596) as a selective neurokinin (NK) 2 and tachykinin receptor antagonist. It is known that tachykinins have been implicated in the pathophysiology of irritable bowel syndrome (IBS) with diarrhoea. Ibodutant was studied as a treatment for gastrointestinal disorders. A phase 2 trial completed in May 2012 with positive results. Ibodutant participated in a 52-week phase 3 in women with IBS with diarrhea, however, the study was terminated because of the negative results of the sister study NAK-06 and the low overall response rate at week 24.
Status:
Investigational
Source:
INN:trimoxamine [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Trimoxamine hydrochloride is an antihypertensive agent.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Streptoniazid is a streptomycin derivative patented by Societe des usines chimiques de Rhone-Poulenc as antibiotic effective against tuberculosis.
Status:
Investigational
Source:
NCT00945282: Phase 2 Interventional Completed Infection, Human Immunodeficiency Virus
(2009)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:mexrenoate potassium [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Mexrenoate potassium is an aldosterone antagonist, which was developed as an antihypertensive agent. However, this drug has never been marketed.
Status:
Investigational
Source:
Eur Respir J. May 1999;13(5):1144-50.: Not Applicable Human clinical trial Completed N/A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Mirincamycin, a protein biosynthesis inhibitor was studied as an antibacterial agent. It was shown that mirincamycin could be promising candidate in the therapy and prophylaxis of multidrug-resistant falciparum malaria. Moreover, in combination with 4 or 8-aminoquinolines it could be used for the treatment and relapse prevention of vivax malaria. In addition, was studied the anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model. However, the negative P. cynomolgi hypnozoite data indicates that mirincamycin is unlikely to have potential as a clinical anti-relapse agent.
Class (Stereo):
CHEMICAL (ACHIRAL)
Pelretin is an antikeratinizing agent that was in phase II trials for the treatment of skin disorders. However, these studies were discontinued. In addition, pelretin was studied in cosmetic as a cream to treat acne and against skin wrinkling. Information about the further development of pelretin is not available.
Status:
Investigational
Source:
NCT01239069: Phase 2 Interventional Completed Dry Eye
(2010)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Tomicorat is an anti-inflammatory agent.
