PELRETIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H28O2
Molecular Weight	336.4672
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	3
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C2=CC=C(C=C2)C(O)=O

InChI

InChIKey=YRNAHKPMDMVFMV-GMICYETFSA-N

InChI=1S/C23H28O2/c1-17(10-15-21-18(2)8-6-16-23(21,3)4)7-5-9-19-11-13-20(14-12-19)22(24)25/h5,7,9-15H,6,8,16H2,1-4H3,(H,24,25)/b9-5+,15-10+,17-7+

HIDE SMILES / InChI

Molecular Formula	C23H28O2
Molecular Weight	336.4672
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	3
Optical Activity	NONE

Description
Sources: https://www.latimes.com/archives/la-xpm-1989-12-11-me-101-story.html | https://adisinsight.springer.com/drugs/800003572

Pelretin is an antikeratinizing agent that was in phase II trials for the treatment of skin disorders. However, these studies were discontinued. In addition, pelretin was studied in cosmetic as a cream to treat acne and against skin wrinkling. Information about the further development of pelretin is not available.

Originator

Approval Year

Sample Use Guides

In Vivo Use Guide

cream

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:22:39 GMT 2023` Edited by `admin` on `Fri Dec 15 18:22:39 GMT 2023`
Record UNII	H9MC68UEZ9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PELRETIN

Official Name

English

RWJ-18704

Code

English

BASF-43915

Code

English

BASF 43915

Code

English

BENZOIC ACID, 4-(4-METHYL-6-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-1,3,5-HEXATRIENYL)-, (E,E,E)-

Common Name

English

PELRETIN [USAN]

Common Name

English

pelretin [INN]

Common Name

English

RWJ 18704

Code

English

ORF 18704

Code

English

ORF-18704

Code

English

(E,E,E)-P-(4-METHYL-6-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-1,3,5-HEXATRIENYL)BENZOIC ACID

Systematic Name

English

Code System Code Type Description

EVMPD

SUB09650MIG