Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H6N2O2 |
| Molecular Weight | 174.1561 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 2 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C(C=C1N=C=O)N=C=O
InChI
InChIKey=DVKJHBMWWAPEIU-UHFFFAOYSA-N
InChI=1S/C9H6N2O2/c1-7-2-3-8(10-5-12)4-9(7)11-6-13/h2-4H,1H3
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. | 2004-08 |
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| Synthesis of metal incorporated low molecular weight polyurethanes from novel aromatic diols, their characterization and bactericidal properties. | 2004-08 |
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| Determination of isocyanates in air using 1-(2-methoxyphenyl)piperazine-impregnated filters: long-term sampling performance and field comparison with impingers with dibutylamine. | 2004-07 |
|
| Hemolysate-filled polyethyleneimine and polyurea microcapsules as potential red blood cell substitutes: effect of aqueous monomer type on properties of the prepared microcapsules. | 2004-06-18 |
|
| Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. | 2004-06 |
|
| Nerve growth factor and substance P regulation in nasal sensory neurons after toluene diisocyanate exposure. | 2004-06 |
|
| Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma. | 2004-05 |
|
| Cancer incidence and mortality of isocyanate exposed workers from the Swedish polyurethane foam industry: updated findings 1959-98. | 2004-05 |
|
| MMNTP-a new tailor-made modular derivatization agent for the selective determination of isocyanates and diisocyanates. | 2004-04 |
|
| Increase in the level of histidine decarboxylase mRNA expression in nasal mucosa of rats sensitized by toluene diisocyanate. | 2004-03 |
|
| Up-regulation of histamine H(1) receptors in an allergic rat nasal mucosa model. | 2004-03 |
|
| Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions. | 2004-02-15 |
|
| Imbalance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in toluene diisocyanate-induced asthma. | 2004-02 |
|
| Determination of unreacted 2,4-toluene diisocyanate (2,4TDI) and 2,6-toluene diisocyanate (2,6TDI) in foams at ultratrace level by using HPLC-CIS-MS-MS. | 2003-12 |
|
| Exposure to toluene diisocyanate (TDI) induces IL-8 production from bronchial epithelial cells: effect of pro-inflammatory cytokines. | 2003-12 |
|
| Effects of cilomilast on dendritic cell function in contact sensitivity and dendritic cell migration through skin. | 2003-11-28 |
|
| Toluene diisocyanate exposure induces laryngo-tracheal eosinophilia, which can be ameliorated by supplementation with antioxidant vitamins in guinea pigs. | 2003-10 |
|
| Simultaneous sampling of gas- and aerosol-phase TDI with a triple filter system. | 2003-10 |
|
| Localization of inducible nitric oxide synthase and endothelial constitutive nitric oxide synthase in airway mucosa of toluene diisocyanate-induced asthma. | 2003-09-17 |
|
| Delayed type allergic itch-associated response induced by toluene-2,4-diisocyanate in hairless mice. | 2003-09 |
|
| Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate. | 2003-08-29 |
|
| AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis. | 2003-08 |
|
| Capillary electrochromatographic separation of enantiomers on chemically bonded type of cellulose derivative chiral stationary phases with a positively charged spacer. | 2003-08 |
|
| Evaluation of organic-vapor respirator cartridge efficiency for toluene diisocyanate vapor in the presence of methylenechloride or acetone solvent. | 2003-08 |
|
| Methods for the identification of chemical respiratory allergens in rodents: comparisons of cytokine profiling with induced changes in serum IgE. | 2003-07-29 |
|
| [Effect and mechanism of bishudiwan(BSDW) against allergy]. | 2003-06 |
|
| Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate. | 2003-06 |
|
| Matrix metalloproteinase inhibitor regulates inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression in a murine model of toluene diisocyanate-induced asthma. | 2003-06 |
|
| A nonradioisotopic endpoint for measurement of lymph node cell proliferation in a murine allergic contact dermatitis model, using bromodeoxyuridine immunohistochemistry. | 2003-05-17 |
|
| A 17-year epidemiological study on changes in lung function in toluene diisocyanate foam workers. | 2003-05 |
|
| Effect of FK3657, a non-peptide bradykinin B2 receptor antagonist, on allergic airway disease models. | 2003-04-25 |
|
| Long-term follow-up of toluene diisocyanate-induced asthma. | 2003-04 |
|
| Effects of thermal degradation products from polyurethane foams based on toluene diisocyanate and diphenylmethane diisocyanate on isolated, perfused lung of guinea pig. | 2003-04 |
|
| Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge. | 2003-04 |
|
| Evaluation of denuder sampling for a mixture of three common gaseous diisocyanates. | 2003-03 |
|
| Therapeutic effects of interleukin-1 receptor antagonist on allergic rhinitis of guinea pig. | 2003-03 |
|
| Investigation of the competitive rate of derivatization of several secondary amines with phenylisocyanate (PHI), hexamethylene-1,6-diisocyanate (HDI), 4,4'-methylenebis(phenyl isocyanate) (MDI) and toluene diisocyanate (TDI) in liquid medium. | 2003-02 |
|
| Identification and quantification of in vitro adduct formation between protein reactive xenobiotics and a lysine-containing model peptide. | 2003-02 |
|
| Clinical findings for residents near a polyurethane foam manufacturing plant. | 2003-01-01 |
|
| Fate and potential environmental effects of methylenediphenyl diisocyanate and toluene diisocyanate released into the atmosphere. | 2003-01 |
|
| Metalloproteinase-9 is increased after toluene diisocyanate exposure in the induced sputum from patients with toluene diisocyanate-induced asthma. | 2003-01 |
|
| Respiratory effects of toluene diisocyanate in the workplace: a discussion of exposure-response relationships. | 2003 |
|
| Longitudinal study of specific antibodies to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in patients with TDI-induced asthma. | 2002-12 |
|
| Evaluation of self-reported skin problems among workers exposed to toluene diisocyanate (TDI) at a foam manufacturing facility. | 2002-12 |
|
| Occupational asthma, lung function decrement, and toluene diisocyanate (TDI) exposure: a critical review of exposure-response relationships. | 2002-12 |
|
| Frequency and trends of occupational asthma due to toluene diisocyanate: a critical review. | 2002-12 |
|
| Industrial hygiene sampling for airborne TDI in six flexible slabstock foam manufacturing facilities in the United States: a comparison of the short-term and long-term sampling data. | 2002-12 |
|
| Toxicology of toluene diisocyanate. | 2002-12 |
|
| [Functional and morphological observation on cells in allergic rhinitis guinea-pigs with cold or heat syndrome]. | 2001-03 |
|
| [Model experiments of physiologic and pharmacologic interactions with epithelial ionic currents induced by stimulation of sensory receptors ]. | 2001 |
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17X7AFZ1GH
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209-544-5
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m10959
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DTXSID7026156
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SUBSTANCE RECORD
