STREPTONIAZID

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H44N10O12
Molecular Weight	700.6981
Optical Activity	UNSPECIFIED
Defined Stereocenters	15 / 15
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]2(O[C@H]1[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]1NC(N)=N)O[C@@H](C)[C@](O)(C=NNC(=O)C3=CC=NC=C3)[C@H]2O[C@]4([H])O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]4NC

InChI

InChIKey=JCBKYEIGGFKWPQ-HKWRBIJSSA-N

InChI=1S/C27H44N10O12/c1-9-27(45,8-34-37-22(44)10-3-5-33-6-4-10)21(49-23-14(32-2)18(42)15(39)11(7-38)47-23)24(46-9)48-20-13(36-26(30)31)16(40)12(35-25(28)29)17(41)19(20)43/h3-6,8-9,11-21,23-24,32,38-43,45H,7H2,1-2H3,(H,37,44)(H4,28,29,35)(H4,30,31,36)/b34-8+/t9-,11-,12+,13-,14-,15-,16+,17-,18-,19+,20+,21-,23-,24-,27+/m0/s1

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14358296 | https://www.ncbi.nlm.nih.gov/pubmed/13268856

Streptoniazid is a streptomycin derivative patented by Societe des usines chimiques de Rhone-Poulenc as antibiotic effective against tuberculosis.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Clinical and biological study of streptoniazid].	1954	14358296
The intermittent use of streptomycin and isoniazid singly and together in murine leprosy.	1955 Dec	13268856

Patents

Name

Type

Language

STREPTONIAZID

Official Name

English

NSC-77675

Code

English

Streptoniazid [WHO-DD]

Common Name

English

ISONICOTINIC ACID HYDRAZIDE, HYDRAZONE WITH STREPTOMYCIN

Common Name

English

D-STREPTAMINE, O-2-DEOXY-2-(METHYLAMINO)-.ALPHA.-L-GLUCOPYRANOSYL-(1-2)-O-5-DEOXY-3-C-(((4-PYRIDINYLCARBONYL)HYDRAZONO)METHYL)-.ALPHA.-L-LYXOFURANOSYL-(1-4)-N1,N3-BIS(AMINOIMINOMETHYL)-

Common Name

English

ESTREPTONIAZID

Common Name

English

streptoniazid [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C280