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Restrict the search for
benzyl benzoate
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Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Etilefrine is a cardiac stimulant used as an antihypotensive. Intravenous infusion of this compound increases cardiac output, stroke volume, venous return and blood pressure in man and experimental animals, suggesting stimulation of both α and β adrenergic receptors. However, in vitro studies indicate that etilefrine has a much higher affinity for β1 (cardiac) than for β2 adrenoreceptors. Intravenous etilefrine increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Marked falls in pulse rate, cardiac output, stroke volume and peripheral bloodflow, accompanied by rises in mean arterial pressure, occur when etilefrine is infused after administration of intravenous propranolol 2,5 mg. These findings indicate that etilefrine has both β1 and α1 adrenergic effects in man. The French Health Products Agency concluded that etilefrine and heptaminol have an unfavourable harm-benefit balance, and also placed restrictions on the use of midodrine.
Status:
Possibly Marketed Outside US
Source:
Mandelamine by Walker, J.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
(S)-Mandelic acid (L-Mandelic acid) is an enantiomer of the aromatic alpha hydroxy acid that is used in the production of pharmaceuticals for its antibacterial activity and administered as an oral antibiotic or a treatment for urinary tract infections. Well-known ester drugs, such as cyclandelate and homatropine, are derived from L-mandelic acid. Because of its antibacterial properties, L-mandelic acid is an alternative to α-hydroxy acids in skin care products. Among the most popular ingredients in both skin care and anti-aging products, L-mandelic acid now represents a multi-billion dollar industry.
Status:
Possibly Marketed Outside US
Source:
Mandelamine by McKenzie, A.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
(R)-Mandelic acid (D-Mandelic acid) is an enantiomer of the aromatic alpha hydroxy acid that is used as a chiral resolving agent, and as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. (R)-(-)-Mandelic acid, is used as an antiseptic ingredient particularly against urinary tract infections.
Status:
Possibly Marketed Outside US
Source:
NCT00160849: Phase 4 Interventional Completed HIV Infections
(2004)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Lopinavir D-Valine Diastereomer, a selective HIV protease inhibitor, possesses similar properties with lopinavir.
Status:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Estriol acetate benzoate is a semisynthetic, steroidal estrogen. Estriol benzoate diacetate is reported as an ingredient of Holin in Japan. It is an estrogen receptor agonist.
Status:
Possibly Marketed Outside US
Source:
Japan:Diisobutylaminobenzoyloxypropyl Theophylline
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Xanthine derivative, diisobutylaminobenzoyloxypropyl theophylline (Vestphyllin), is a vasodilator, bronchodilator.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Lappaconitine is an alkaloid isolated from the root of Aconltitum sinomantanum Nakai. It has a strong analgesic activity that does not involve the opioid receptor. It was shown to have class-I antiarrhythmic action and irreversibly blocks cloned human heart (hH1) channels by binding to the site 2 receptor.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Silver benzoate is a water soluble crystalline salt composed of silver and benzoic acid with the formula C7H5AgO2 with marked antimicrobial activity. Silver benzoate can be used in synthesis of silver nanoparticle, and in the synthesis of triphenyltinbenzoate. Silver benzoate along with 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD) is an efficient catalytic system for the reaction of carbon dioxide with various ketones.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Amidoflumet is a trifluoromethanesulfonanilide compound with high house dust miticidal activity which was discovered by Sumitomo Chemical, and was registered in Japan in 2004. House dust mites and their products
are known to be major household allergens to children and the elderly, and they cause asthma and atopic dermatitis. Amidoflumet shows high lethal activity against common house dust mites.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Dimetofrine is a selective agonist of post-synaptic a1-adrenergic receptors. The drug was investigated as a cardiostimulant to treat orthostatic hypotension. Clinical investigation showed that dimetofrine relieves asthenia, paleness, drowsiness, fatigue, headache and other symptoms associated with hypotension. It was observed, that in acidic conditions similar to conditions in the stomach, dimetofrine is able to react with nitrites with the formation of highly mutagenic compound 2,6-dimethoxy-1,4-benzoquinone (DMBQ).