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Details

Stereochemistry ACHIRAL
Molecular Formula C9H7ClF3NO4S
Molecular Weight 317.669
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMIDOFLUMET

SMILES

COC(=O)C1=CC(Cl)=CC=C1NS(=O)(=O)C(F)(F)F

InChI

InChIKey=KBHDSWIXRODKSZ-UHFFFAOYSA-N
InChI=1S/C9H7ClF3NO4S/c1-18-8(15)6-4-5(10)2-3-7(6)14-19(16,17)9(11,12)13/h2-4,14H,1H3

HIDE SMILES / InChI
Molecular Formula C9H7ClF3NO4S
Molecular Weight 317.669
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/?term=14981308 and https://books.google.ru/books?id=4023BgAAQBAJ&pg=PA96&lpg=PA96&dq=AMIDOFLUMET&source=bl&ots=fWQsyYEL2f&sig=kyMHTNXU9wkB1ml97pATA7N_Z28&hl=en&sa=X&ved=0ahUKEwi7h5T35bPPAhXFjywKHahyCMc4ChDoAQg7MAU#v=onepage&q=AMIDOFLUMET&f=false Retrieved from The Toxicology and Biochemistry of Insecticides, Second Edition By Simon J. Yu, p.96

Amidoflumet is a trifluoromethanesulfonanilide compound with high house dust miticidal activity which was discovered by Sumitomo Chemical, and was registered in Japan in 2004. House dust mites and their products are known to be major household allergens to children and the elderly, and they cause asthma and atopic dermatitis. Amidoflumet shows high lethal activity against common house dust mites.

Originator

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Dermatophagoides farinae viability
1
Target ID: Dermatophagoides farinae viability
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Patents

Patents

JP2006123961A
1
JP2008509189A
188
JP2011509971A
151
JP2011526599A
45
JP2011527307A
41
JP2012500824A
79

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:41:18 GMT 2023
Edited
by admin
on Fri Dec 15 19:41:18 GMT 2023
Record UNII
N8D88V49HD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMIDOFLUMET
ISO   JAN  
Common Name English
AMIDOFLUMET [JAN]
Common Name English
2-(TRIFLUOROMETHYLSULFONYLAMINO)-5-CHLOROBENZOIC ACID METHYL ESTER
Systematic Name English
AMIDOFLUMET [ISO]
Common Name English
METHYL 5-CHLORO-2-(((TRIFLUOROMETHYL)SULFONYL)AMINO)BENZOATE
Systematic Name English
5-CHLORO-2-(TRIFLUOROMETHYLSULFONYLAMINO)BENZOIC ACID METHYL ESTER
Systematic Name English
Code System Code Type Description
CAS
84466-05-7
Created by admin on Fri Dec 15 19:41:18 GMT 2023 , Edited by admin on Fri Dec 15 19:41:18 GMT 2023
PRIMARY
EPA CompTox
DTXSID9057842
Created by admin on Fri Dec 15 19:41:18 GMT 2023 , Edited by admin on Fri Dec 15 19:41:18 GMT 2023
PRIMARY
ALANWOOD
amidoflumet
Created by admin on Fri Dec 15 19:41:18 GMT 2023 , Edited by admin on Fri Dec 15 19:41:18 GMT 2023
PRIMARY
FDA UNII
N8D88V49HD
Created by admin on Fri Dec 15 19:41:18 GMT 2023 , Edited by admin on Fri Dec 15 19:41:18 GMT 2023
PRIMARY
PUBCHEM
9861780
Created by admin on Fri Dec 15 19:41:18 GMT 2023 , Edited by admin on Fri Dec 15 19:41:18 GMT 2023
PRIMARY
NIH
NCATS
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