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Details

Stereochemistry ABSOLUTE
Molecular Formula C37H48N4O5
Molecular Weight 628.8008
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LOPINAVIR, D-VALINE DIASTEREOMER-

SMILES

CC(C)[C@@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC2=CC=CC=C2)NC(=O)COC3=C(C)C=CC=C3C)CC4=CC=CC=C4

InChI

InChIKey=KJHKTHWMRKYKJE-UQJYGFKOSA-N
InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34+/m0/s1

HIDE SMILES / InChI

Description

Lopinavir D-Valine Diastereomer, a selective HIV protease inhibitor, possesses similar properties with lopinavir.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
LOPINAVIR, D-VALINE DIASTEREOMER-
Common Name English
LOPINAVIR IMPURITY, LOPINAVIR D- VALINE DIASTEREOMER-
USP  
Common Name English
LOPINAVIR IMPURITY K [EP IMPURITY]
Common Name English
LOPINAVIR, (R-(2S,4S,5S))-
Common Name English
LOPINAVIR, (R)-
Common Name English
LOPINAVIR IMPURITY, LOPINAVIR D- VALINE DIASTEREOMER- [USP IMPURITY]
Common Name English
(2R)-N-((1S,3S,4S)-1-BENZYL-4-((2-(2,6-DIMETHYLPHENOXY)ACETYL)AMINO)-3-HYDROXY-5-PHENYLPENTYL)-3-METHYL-2-(2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)BUTANAMIDE
Systematic Name English
LOPINAVIR D- VALINE DIASTEREOMER
Common Name English
N-((2S,4S,5S)-5-(2-(2,6-DIMETHYLPHENOXY)ACETAMIDO)-4-HYDROXY-1,6-DIPHENYLHEXAN-2-YL)-3-METHYL-2-(2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)BUTANAMIDE, (R)-
Common Name English
Code System Code Type Description
PUBCHEM
6850809
Created by admin on Sat Dec 16 07:57:09 GMT 2023 , Edited by admin on Sat Dec 16 07:57:09 GMT 2023
PRIMARY
FDA UNII
13246C84TX
Created by admin on Sat Dec 16 07:57:09 GMT 2023 , Edited by admin on Sat Dec 16 07:57:09 GMT 2023
PRIMARY
NIH
NCATS
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