Niprofazone is an anti-inflammatory analgesic.

Pyrroliphene is a dialkylaminodiphenylbutanol ester with antitussive and analgesic activities. In clinical trials the major side effect of Pyrroliphene was sedation, and the other side effect liabilities were similar to those of morphine.

Cogazocine is an opioid analgesic of the benzomorphan family, invented by the Dutch company ACF Chemiedfarma N.V. The compound was active in a tail withdrawal and writhing tests in rats and possessed nalorphine-like activity in rats after an intravenous dose of 0.04 mg/kg.

Nixylic acid, an anilinonicotinic acid derivative, is an anti-inflammatory agent.

Darsidomine sydnonimine derivative, which serves as NO donor. Administration of darsidomine causes selective dilation of the coronary artery. The drug has an anti-ischemic action without inducing tolerance on long-term administration.

Enprofylline is a xanthine derivative that shares theophylline's bronchodilator properties. It can be considered a relatively selective, though not potent adenosine A2B receptors antagonist. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with the elevation in liver enzyme levels and unpredictable blood levels.

Etosalamide (O-(2-ethoxyethoxy)benzamid) is salicylamide derivative, that undervent metabolic transformation to O-carbamoylphenoxyaceticacid in human body. The physiological and toxicological properties of this compound have not been evaluated.

Etonitazene is a potent and selective mu-opioid agonist. It was developed in CIBA. Administration of etonitazene may induce respiratory depression, and therefor etonitazene is not used in humans. Etonitazene is explicitly listed as an illegal drug under UN convention and is illegal throughout the world.

Losmiprofen is a nonsteroidal anti-inflammatory and analgesic agent.

Betaprodine is an opioid analgesic under international control according to the UN Single Convention 1961. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures.