U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 201 - 210 of 444 results

mixture
Status:
US Approved OTC
Source:
21 CFR 349.12(c) ophthalmic:demulcents gelatin
Source URL:
First marketed in 1921

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
21 CFR 310.527(a) hair loss prevention polysorbate 60
Source URL:
First approved in 1938
Source:
Belladonna and Opium by Bryant Ranch Prepack
Source URL:

Class:
MIXTURE

mixture
Status:
Possibly Marketed Outside US
Source:
NCT00754247: Phase 4 Interventional Completed Keloid
(2006)
Source URL:
First approved in 2004

Class:
MIXTURE

mixture
Status:
Possibly Marketed Outside US
First approved in 1941
Source:
Morphine Sulfate by Bryant Ranch Prepack
Source URL:

Class:
MIXTURE

Status:
US Previously Marketed
Source:
NPH Iletin by Lilly
(1950)
Source URL:
First approved in 1950
Source:
NPH Iletin by Lilly
Source URL:

Class:
PROTEIN


Insulin Pork is Insulin isolated from pig pancreas. Insulin is a hormone secreted by the beta cells of the pancreas to help move glucose from the blood into body cells for energy. People with Type 1 diabetes lose the ability to produce insulin and must inject it. In the past, all commercially available insulin came from the pancreases of cows or pigs. Pork and beef insulins are similar to human insulin, differing only in one or a few amino acids. However, even a slight difference is enough to elicit an allergic response in some people. To overcome this problem, researchers looked for ways to make insulin that would more closely resemble human insulin.
Status:
US Approved OTC
Source:
21 CFR 349.12(d)(4) ophthalmic:demulcents polysorbate 80
Source URL:
First approved in 1949
Source:
Olothorb by Merck Sharp & Dohme
Source URL:

Class:
POLYMER


Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the manufacture of the popular antiarrhythmic amiodarone. Polysorbate 80 is also used as an excipient in some European and Canadian influenza vaccines. Influenza vaccines contain 25 μg of polysorbate 80 per dose. Polysorbate 80 is also used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth. It is also used as an emulsifier in the estrogen-regulating drug Estrasorb. In Europe and America, people eat about 100 mg of polysorbate 80 in foods per day on average. Polysorbate 80 has not been found to be carcinogenic. Rats fed with diets containing up to 5% polysorbate 80 by volume for 12 weeks showed no toxic effects.

Showing 201 - 210 of 444 results