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m sacubitril
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Rebaudioside C is a natural primary glycoside constituent of the plant Stevia rebaudiana Bertoni and used as natural non-caloric sweeteners to diabetics and others on carbohydrate-controlled diets. Found in the by-product of Rebaudioside A production, Rebaudioside C is produced through advanced glycoside isolation and specialized extraction processing. While not a sweetener itself, Rebaudioside C has been trialed with nutritive sweeteners and shown to enable a 20-25% reduction in calories. In preclinical studies Rebaudioside C shows potent anti-inflammatory activity in against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. Steviol glycosides have not yet been approved as a sweetener in the European Union, but purified rebaudioside A gained GRAS (Generally Recognized as Safe) status in the USA in 2008, and in the same year the Joint FAO/WHO Expert Committee on Food Additives suggested a temporary admissible daily intake (ADI) of 0–4 mg/kg body weight, expressed as steviol.
Status:
Other
Class (Stereo):
CHEMICAL (EPIMERIC)
Conditions:
Destomycin A is an aminoglycoside antibiotic and is reported to have antibacterial and anthelmintic activity. It has an antibacterial effect on Gram-positive bacteria, Gram-negative bacteria, and fungi. The mode of action of destomycin A is the inhibition of polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in several animal tissues. Destomycin A is added to feed for pigs and chickens to prevent parasitic infection of Ascaris suum (the mechanism of action involves inhibition of vitelline coat formation of the parasite eggs.)
