U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 11 - 20 of 4645 results

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure.
Cyclophosphamide (the generic name for Cytoxan, Neosar, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. It is used to treat various types of cancer and some autoimmune disorders. It is a "prodrug"; it is converted in the liver to active forms that have chemotherapeutic activity
Status:
First approved in 1953
Source:
BIOMYDRIN W/HC THONZONIUM BROMIDE by BW
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Thonzonium Bromide is a cationic surface-active compound. As an additive to pharmacologic formulations, thonzonium bromide causes dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. Thonzonium bromide is a component of FDA-approved Coly-Mycin S Otic, used for treating infections of the ear caused by certain bacteria. It has being shown that Thonzonium bromide inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo, suggesting that Thonzonium bromide might be a useful alternative therapy in preventing or treating osteolytic diseases..
Status:
US Approved OTC
Source:
21 CFR 331.11(g)(3) antacid:magnesium-containing magnesium aluminosilicate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Magnesium aluminosilicate is an antacid, it is used in combination with magnesium hydroxide to relieve heartburn.
Status:
US Approved OTC
Source:
21 CFR 331.11(g)(2) antacid:magnesium-containing magaldrate
Source URL:
First approved in 1960
Source:
Riopan by Ayerst
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Almagodrate anhydrous is an antacid.
Status:
US Approved OTC
Source:
21 CFR 332.10 antiflatulent simethicone
Source URL:
First approved in 1952
Source:
Mylicon by Stuart
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Silicon dioxide (silica) is most commonly found in nature as quartz, as well as in various living organisms. Silicon dioxide one of the most complex and most abundant families of materials, existing both as several minerals and being produced synthetically. In food and pharmaceutical industry silica is a common additive, where it is used primarily as a flow in powdered foods, or to adsorb water in hygroscopic application. In pharmaceutical products, silica aids powder flow when tablets are formed.
Status:
US Animal Drug
Source:
21 CFR 520.1802a PART 520-ORAL DOSAGE FORM NEW ANIMAL DRUGS piperazine-carbon disulfide complex
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Picadex is a dithiocarbamate derivative of piperazine. It was used in veterinary as an antihelmintic drug. It was shown to be effective in the treatment of Oesophagostamum infection in pigs.
Status:
US Animal Drug
Source:
GREEN BOOK:FLUMETHASONE ACETATE [GREEN BOOK]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Flumethasone 21-acetate is an anti-inflammatory corticosteroid. It has 300 times greater anti-inflammatory activity and 677 times greater capacity to promote liver glycogen deposition than hydrocortisone. It has anti-rheumatic potency 31 times higher than cortisol.
Status:
Investigational
Source:
NCT04419948: Not Applicable Interventional Unknown status Diabetes Mellitus, Adult-Onset
(2019)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
Am J Dent. Feb 2002;15(1):8-10.: Phase 2 Human clinical trial Completed N/A
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Showing 11 - 20 of 4645 results