ABIVERTINIB

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H26FN7O2
Molecular Weight	487.5287
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCN(CC1)C2=C(F)C=C(NC3=NC(OC4=CC=CC(NC(=O)C=C)=C4)=C5C=CNC5=N3)C=C2

InChI

InChIKey=UOFYSRZSLXWIQB-UHFFFAOYSA-N

InChI=1S/C26H26FN7O2/c1-3-23(35)29-17-5-4-6-19(15-17)36-25-20-9-10-28-24(20)31-26(32-25)30-18-7-8-22(21(27)16-18)34-13-11-33(2)12-14-34/h3-10,15-16H,1,11-14H2,2H3,(H,29,35)(H2,28,30,31,32)

HIDE SMILES / InChI

Molecular Formula	C26H26FN7O2
Molecular Weight	487.5287
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Epidermal growth factor receptor 46 Target ID: CHEMBL2363049 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28414972	Inhibitor 8297

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:59:54 GMT 2023` Edited by `admin` on `Sat Dec 16 18:59:54 GMT 2023`
Record UNII	CER0OPG92L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ABIVERTINIB

Official Name

English

AC-0010

Code

English

Avitinib [WHO-DD]

Common Name

English

AC0010

Code

English

EX-ACEA0010

Code

English

ACEA100610

Code

English

A610

Code

English

Abivertinib [WHO-DD]

Common Name

English

2-PROPENAMIDE, N-(3-((2-((3-FLUORO-4-(4-METHYL-1-PIPERAZINYL)PHENYL)AMINO)-7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)OXY)PHENYL)-

Systematic Name

English

ABIVERTINIB [USAN]

Common Name

English

N-{3-[(2-{[3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide

Systematic Name

English

AVITINIB

Common Name

English

abivertinib [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1967