U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 11 - 20 of 40 results

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


(2R)-2-epi-Perindopril is an epimer (R, SS, SS) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This form of the drug is almost inactive.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)


(±)-1'',7A-di-epi-Perindopril is a mixture of two isomers (S, SR, SR) and (R, RS, RS). The first of which is a less active epimer of the antihypertensive drug perindopril, while the second one is almost completely inactive.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)


(1''R,2'R)-1'',2'-di-epi-Perindopril is an epimer (S, SS, RR) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This epimer is a nearly inactive form of the drug.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)



(3AR)-3A-epi-Perindopril is an epimer (S, RS, SS) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This epimer possesses equal activity with the parent compound, perindopril.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)



(7AR)-7A-epi-Perindopril is an epimer (S, SR, SS) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This epimer possesses equal activity with the perindopril.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)


(1''R)-1''-epi-Perindopril is an epimer of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. (1''R)-1''-epe-Perindopril has configuration S, SS, SR and is less active than the parent drug.
Status:
US Previously Marketed
First approved in 2015

Class (Stereo):
CHEMICAL (ABSOLUTE)



Perindopril arginine is a stable L-arginine salt of perindopril. Perindopril, a pro-drug, is hydrolyzed to perindoprilat, which inhibits ACE in humans and in animals. It is indicated for the treatment of hypertension, heart failure and coronary artery disease. Perindopril arginine may be used in monotherapy or in combination with other classes of antihypertensive therapy.

Showing 11 - 20 of 40 results