1''-EPI-PERINDOPRIL, (±)-

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H32N2O5
Molecular Weight	368.4678
Optical Activity	( + / - )
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC[C@@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC

InChI

InChIKey=IPVQLZZIHOAWMC-QMHWVQJVSA-N

InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14+,15-,16-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1457697

(1''R)-1''-epi-Perindopril is an epimer of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. (1''R)-1''-epe-Perindopril has configuration S, SS, SR and is less active than the parent drug.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596
Unknown 2596

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

PERINDOPRIL TERT-BUTYLAMINE IMPURITY I [EP IMPURITY]

Preferred Name

English

1''-EPI-PERINDOPRIL, (±)-

Common Name

English

(2RS,3ARS,7ARS)-1-((2RS)-2-(((1SR)-1-(ETHOXYCARBONYL)BUTYL)AMINO)PROPANOYL)OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID

Systematic Name

English

Code System Code Type Description

FDA UNII

7327NJ3271

Created by admin on Mon Mar 31 21:56:25 GMT 2025 , Edited by admin on Mon Mar 31 21:56:25 GMT 2025

PRIMARY

SUBSTANCE RECORD


					7327NJ3271

1''-EPI-PERINDOPRIL, (±)-

Details

SMILES

InChI

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/1457697

Approval Year

Conditions

Sample Use Guides

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1457697