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Details

Stereochemistry RACEMIC
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity ( + / - )
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 7A-EPI-PERINDOPRIL, (±)-

SMILES

[H][C@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@]1([H])CCCC2)C(O)=O

InChI

InChIKey=IPVQLZZIHOAWMC-GVRJEKJASA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15+,16-/m0/s1

HIDE SMILES / InChI
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

(±)-7A-epi-Perindopril is a mixture of two isomers (S, SR, SS) and (R, RS, RR) each of which is an isomer of the antihypertensive drug perindopril. The first of which has the same activity as the parent compound while the second one is almost inactive.

CNS Activity

CNS Non-penetrant
1014

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
dog: 1 mg/kg
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:12:30 UTC 2023
Edited
by admin
on Sat Dec 16 08:12:30 UTC 2023
Record UNII
OQ0911H5P0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
7A-EPI-PERINDOPRIL, (±)-
Common Name English
(2RS,3ARS,7ASR)-1-((2RS)-2-(((1RS)-1-(ETHOXYCARBONYL)BUTYL)AMINO)PROPANOYL)OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID
Systematic Name English
PERINDOPRIL TERT-BUTYLAMINE IMPURITY Q [EP IMPURITY]
Common Name English
(±)-7A-EPI-PERINDOPRIL
Common Name English
Code System Code Type Description
FDA UNII
OQ0911H5P0
Created by admin on Sat Dec 16 08:12:30 UTC 2023 , Edited by admin on Sat Dec 16 08:12:30 UTC 2023
PRIMARY
PUBCHEM
72941688
Created by admin on Sat Dec 16 08:12:30 UTC 2023 , Edited by admin on Sat Dec 16 08:12:30 UTC 2023
PRIMARY
Related Record Type Details
Structure of PERINDOPRIL ERBUMINE
PARENT -> IMPURITY
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
NIH
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