U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 11 - 20 of 25 results

Status:
US Previously Marketed
Source:
Seldane by Dow
(1985)
Source URL:
First approved in 1985
Source:
Seldane by Dow
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Terfenadine under brand name Seldane was used for the treatment of allergic rhinitis and allergic skin disorders but was withdrawn because of the serious side effect, heart rhythm problems. Terfenadine is a potent antagonist of histamine H1-receptor-mediated responses.
Status:
US Previously Marketed
Source:
FRENQUEL 20MG by MERRELL
(1961)
Source URL:
First approved in 1955
Source:
Frenquel by Merrell (MerrellNational)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Azacyclonol (aka gamma-pipradrol) is an ataractive agent; a compound which diminished hallucinations in psychotic individuals. It is sometimes referred to as a tranquilizer or antipsychotic, though it does not actually possess these properties. It was used in Europe during the 1950's for treatment of schizophrenia; likely to reduce the psychedelic effects of LSD and mescaline. However, it had mixed clinical effectiveness and did not gain widespread adoption and was eventually discontinued. Azacyclonol was sold under several trade names: Ataractan, Calmeran, Frenoton, Frenquel and Psychosan.
Status:
Possibly Marketed Outside US
Source:
UK NHS:Mizolastine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Mizolastine (Mizollen) is a long-acting H1 -antihistamine indicated for the symptomatic relief of seasonal allergic rhinoconjunctivitis (hay fever), perennial allergic rhinoconjunctivitis and urticaria. It blocks H1 receptors and is commonly fast-acting. It does not prevent the actual release of histamine from mast cells, just prevents it binding to receptors. Side effects can include dry mouth and throat
mixture
Status:
Possibly Marketed Outside US
Source:
Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]
Source URL:

Class:
MIXTURE

Showing 11 - 20 of 25 results