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Restrict the search for
cephalexin
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
Thera Derm by Manna Omni International Incorporated
Source URL:
First approved in 2017
Source:
Thera Derm by Manna Omni International Incorporated
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
7-Aminodesacetoxycephalosporanic acid is a key intermediate for the synthesis of cephalosporins antibiotics and their intermediates. The current process for producing 7-ADCA involves a multistep chemical ring expansion of penicillin G to phenylacetyl-7-ADCA, from which the aromatic side chain is removed using a penicillin acylase.
Status:
Possibly Marketed Outside US
Source:
NCT02683863: Phase 4 Interventional Completed Multiple Sclerosis
(2015)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]
Source URL:
First approved in 2013
Source:
BLA125416
Source URL:
Class:
MIXTURE
Status:
US Approved Rx
(2005)
Source:
ANDA065253
(2005)
Source URL:
First approved in 1971
Source:
KEFLEX by PRAGMA
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Cephalexin is a semisynthetic cephalosporin antibiotic intended for
oral administration. In vitro tests demonstrate that the cephalosporins are bactericidal because of their inhibition of cell-wall synthesis. Cephalexin has been shown to be active against most strains of the following microorganisms both in vitro: Staphylococcus aureus (including penicillinase-producing strains), Streptococcus pneumoniae (penicillin-susceptible strains), Streptococcus pyogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella (Branhamella) catarrhalis, Proteus mirabilis. Cephalexin is indicated for the treatment of the respiratory tract, skin and skin structure, bone and genitourinary tract infections when caused by susceptible strains of the designated microorganisms.