U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 181 - 190 of 5117 results

Status:
Investigational
Source:
USAN:Asperlin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Asperlin (also known as U-13,933), a fungal natural product that was isolated from marine-derived fungus Aspergillus sp. SF-5044 and exhibits antifungal and anti-inflammatory properties in vitro. Experiments in vivo have shown that this compound can prevent atherosclerosis through suppressing inflammation rather than ameliorating dyslipidemia. In addition, asperlin can be developed as a potential anti-cancer therapeutics. It shows anti-cancer properties through ROS generation and ATM pathway in human cervical carcinoma cells.
Status:
Investigational
Source:
USAN:LEVALBUTEROL SULFATE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
USAN:Acetyltannic Acid
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Acetyltannic acid is an astringent (intestinal) for foals, calves, dogs. It is used for treatment of diarrhoea.
Status:
Investigational
Source:
INN:ioglucomide
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Ioglucomide is triiodoanilide derivative patented by Mallinckrodt, Inc. as nonionic x-ray contrast media for myelography. In preclinical studies the efficacy of ioglucomide and metrizamide were comparable. However, acute toxicity after intravenous injection or installation into cerebrospinal fluid was significantly less for ioglucomide. Also, in contrast to metrizamide, ioglucomide produced no evidence of any type of convulsive activity after subarachnoid administration.
Status:
Investigational
Source:
INN:fludorex
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

FLUDOREX is an antiemetic and anorexic agent.
Status:
Investigational
Source:
INN:rifamide
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Rifamides (NSC-143418) are drugs used in the treatment of tuberculosis. They also have immunosuppressive activity, the exact mechanism of which is still unknown, although the ability of rifamides to inhibit tumor necrosis factor (TNF)-induced NF-kB activation may be associated with it. A variety of rifamide analogues exist, such as rifamycin B, rifapentine, rifamycin SV, rifabutin and rifampicin.
Status:
Investigational
Source:
INN:tocofenoxate [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Tocofenoxate is a semisynthetic tocopherol derivative. Vitamin E supplement.
Status:
Investigational
Source:
INN:odalprofen
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Odalprofen was used as an analgesic. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:hydroxypethidine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Hydroxypethidine, an opioid analgesic is an opioid receptor agonist. Hydroxypethidine is under the control of narcotic drugs according to US Single Convention 1961.
Status:
Investigational
Source:
INN:estrofurate
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Estrofurate (AY-11483) is an impeded estrogen. it prevents ovulation and implantation.