ESTROFURATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H26O4
Molecular Weight	378.4608
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC[C@@](O)(C3=COC=C3)[C@@]1(C)CC[C@]4([H])C5=CC=C(OC(C)=O)C=C5CC=C24

InChI

InChIKey=AEVUURWLDCELOV-AYVPJYCDSA-N

InChI=1S/C24H26O4/c1-15(25)28-18-4-6-19-16(13-18)3-5-21-20(19)7-10-23(2)22(21)8-11-24(23,26)17-9-12-27-14-17/h4-6,9,12-14,20,22,26H,3,7-8,10-11H2,1-2H3/t20-,22+,23+,24-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C24H26O4
Molecular Weight	378.4608
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://link.springer.com/chapter/10.1007%2F978-1-4757-2085-3_5 | https://www.ncbi.nlm.nih.gov/pubmed/1120993 | https://www.ncbi.nlm.nih.gov/pubmed/5421116 | https://www.ncbi.nlm.nih.gov/pubmed/4182486

Estrofurate (AY-11483) is an impeded estrogen. it prevents ovulation and implantation.

Originator

Approval Year

PubMed

Title	Date	PubMed
Orally active oestrogens and progestins in prevention of pregnancy in rats.	1969 Apr	4182486
AY-11483, a new type of orally active oestrogen.	1970 Jun	5421116
Synthesis and biological properties of 17 alpha-furylestradiol and dihydroequilin derivatives.	1975 Feb	1120993

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:38:49 GMT 2023` Edited by `admin` on `Fri Dec 15 16:38:49 GMT 2023`
Record UNII	0CDE7T54KW
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ESTROFURATE

Official Name

English

19,24-DINORCHOLA-1,3,5(10),7,20,22-HEXAENE-3,17-DIOL, 21,23-EPOXY-, 3-ACETATE, (17.ALPHA.)-

Common Name

English

estrofurate [INN]

Common Name

English

ESTROFURATE [USAN]

Common Name

English

AY-11483

Code

English

AY-11,483

Code

English

21,23-Epoxy-19,24-dinor-17α-chola-1,3,5(10),7,20,22-hexaene-3,17-diol 3-acetate

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2181