U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

Showing 171 - 180 of 1923 results

Status:
Investigational
Source:
INN:piridicillin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Piridicillin is the semi-synthetic penicillin. It has exhibited broad-spectrum activity in vitro against gram-positive cocci, except penicillin G-resistant Staphylococcus aureus, and against gram-negative bacilli. Piridicillin is reported to be more active in-vitro than piperacillin, azlocillin or ticarcillin against Ps. aeruginosa. It is unstable at alkaline pH and displays marked inoculum independence.
Status:
Investigational
Source:
INN:rotamicillin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

ROTAMICILLIN was developed as an antibiotic that has never been marketed.
Status:
Investigational
Source:
INN:benethamine penicillin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Benethamine penicillin is a medium-long-acting insoluble penicillin salt. After a single injection, this salt acts and bacteriostatic level of penicillin is maintained in the blood for three to six days.
Status:
Investigational
Source:
NCT00854659: Phase 1 Interventional Completed Healthy Volunteers
(2009)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



ABT-102 is a selective antagonist of transient receptor potential vanilloid type 1 (TRPV1), designed for the treatment of nociceptive pain. ABT-102 potently blocks multiple modes of TRPV1 receptor activation and effectively attenuates downstream consequences of receptor activity.
Status:
Investigational
Source:
INN:phenyracillin [INN]
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Phenyracillin is the 2,5-diphenylpiperazine salt of benzylpenicillin. It is antibiotic from Pencillium spp. and also other fungal spp. Shows activity against gram-positive bacteria. Phenyracillin was well tolerated.
Status:
Investigational
Source:
INN:quincarbate
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Quincarbate is a quinoline derivative patented by N. V. Philips' Gloeilampenfabrieken as diuretic. At 12.5 mg/kg orally in rats Quincarbate increased urine excretion by 130%.
Status:
Investigational
Source:
INN:bufrolin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Bufrolin is xanthine derivative and mast cell stabilizer with antiallergic activity. In recent studies, Bufrolin was found to be high potency agonists of human GPR35.
Status:
Investigational
Source:
INN:buzepide metiodide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

N-Methyl Buzepide is diphenylpropane derivative with antisecretory activity.
Status:
Investigational
Source:
INN:fibracillin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

FIBRACILLIN is a semisynthetic antibacterial agent.
Faropenem medoxomil is an ester prodrug derivative of the beta-lactam antibiotic faropenem. The prodrug form of faropenem offers dramatically improved oral bioavailability and leads to higher systemic concentrations of the drug. Faropenem medoxomil is a broad-spectrum antibiotic that is highly resistant to beta-lactamase degradation. It was under development for the treatment of acute bacterial sinusitis, community-acquired pneumonia, acute exacerbation of chronic bronchitis, and uncomplicated skin and skin structure infections.