U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 161 - 170 of 9616 results

Status:
Investigational
Source:
INN:cinametic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cinnamic acid is an odorless white crystalline acid that has only been recently studied for its potential in cancer prevention. Cinnamic acid and its derivatives are the major group of phenolic acids with ubiquitous distribution in fruits and vegetables. Preclinical data support the beneficial effects of Cinnamic acid, including antioxidant, anti-inflammatory, and anti-cancer activities. A more recent botanical review noted that cinnamic acid may help pre-diabetic and diabetic patients. When infected mice were fed food loaded with cinnamic acid, researchers saw that their insulin levels were better managed. Another study which used mice models saw that cinnamic acid improved glucose tolerance by promoting insulin secretion.
Status:
Investigational
Source:
USAN:Aceburic Acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Aceburic acid is the acetyl ester of gamma-hydroxybutyrate (GHB), it has analgesic effects as a prodrug to GHB. GHB is used medically as an anesthetic as well as a treatment for several neurologically affecting diseases.
Status:
Investigational
Source:
INN:broxitalamic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Broxitalamic acid is tribromobenzoic acid derivative used as x-ray contrast medium
Status:
Investigational
Source:
INN:enfenamic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Enfenamic acid (under brand name tromaril) is an anthranilic acid derivative with potent anti-inflammatory, anti-arthritic, analgesic and antipyretic actions. It has additional unique property of anti-platelet aggregation activity, without disturbing any other blood coagulation factors. It also differs from other non-steroidal anti-inflammatory agents like indomethacin, in producing diuresis and natriuresis. In the clinical study, tromaril showed itself as a strong and effective drug for use in various eye diseases.
Status:
Investigational
Source:
INN:cicrotoic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cicrotoic acid is a biochemical drug that acts on bile flow and liquid composition of human bile.
Status:
Investigational
Source:
INN:ioprocemic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ioprocemic Acid is hydrocinnamic acid derivative patented by Schering-Kahlbaum A.-G. as radiographic contrast medium for liver imaging
Status:
Investigational
Source:
INN:tauroselcholic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT00514501: Phase 2 Interventional Completed Acute Coronary Syndrome
(2007)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Iodofiltic Acid I-123 is a single-photon branching free fatty acid radiopharmaceutical with potential application in single-photon emission computed tomography (SPECT). Assessment of fatty acid metabolism by radionuclide techniques has a potential role for the early detection of myocardial ischaemia and the assessment of the severity of ischaemic heart disease. The Iodofiltic Acid I-123 scan is preferable because it can provide suitable information for risk stratification just after an acute myocardial infarction (AMI) without requiring the patient to exercise; it can also detect previous ischaemic insult even after recovery of myocardial perfusion, the so- called "ischaemic memory".
Status:
Investigational
Source:
INN:iosumetic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Iosumetic Acid is a triiodoaminoisophthalic acid derivative patented by Schering A.-G. as contrast medium for direct and indirect lymphography.
Status:
Investigational
Source:
INN:iotrizoic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Iotrizoic Acid is acylated amino acid derivative patented by Swiss pharmaceutical company Cilag-Chemie A.-G. as x-ray contrasting agent