U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 151 - 160 of 391 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Imidazole is a planer five-member heterocyclic ring with 3C and 2N atom and in ring N is present in 1st and 3rd positions. The imidazole ring is a constituent of several important natural products, including purine, histamine, histidine and nucleic acid. Being a polar and ionisable aromatic compound, it improves pharmacokinetic characteristics of lead molecules and thus used as a remedy to optimize solubility and bioavailability parameters of proposed poorly soluble lead molecules. The imidazole derivatives possess extensive spectrum of biological activities such as antibacterial, anticancer, antitubercular, antifungal, analgesic, and anti-HIV activities. The organic compound is used in the chemical industry as an intermediate in the production of pharmaceuticals, pesticides, dye intermediates, auxiliaries for textile dyeing and finishing, photographic chemicals and corrosion inhibitors. The chemical possesses properties (corrosivity to skin, irreversible damage to eyes, teratogenic effects) indicating a hazard for human health. Humans are exposed by consumer products (chemical concentrations up to 10%) and at the workplace. Therefore, the chemical is a candidate for further work. An exposure assessment and if indicated a risk assessment is recommended.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


3-Phenyl-1-propanol is a fragrance ingredient used in many compounds. It may be found in fragrances used in decorative cosmetics, fine fragrances, shampoos, toilet soaps and other toiletries as well as in non-cosmetic products such as household cleaners and detergents. It is a colorless slightly oily liquid, possessing a warm and mild, balsamic-floral, sweet odor of moderate tenacity. This material has been reported to occur in nature, with highest quantities observed in Guava and Feyoa. The worldwide volume of use for 3-phenyl-1-propanol is in the region of 100–1000 metric tons per year. 3-Phenyl-1-propanol was used to study the hydrogenation of trans-cinnamaldehyde using water-soluble organometallic complexes. It was used as starting reagent during the enantioselective synthesis of (S)- and (R)-dapoxetine.
Status:
Possibly Marketed Outside US
Source:
Celladix C.E.F ADVANCED BRIGHTENING AMPOULE by 2359 US INC
(2023)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US
First approved in 2010
Source:
TL G-Fol OS by Trigen Laboratories, Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Boron citrate is a part of triple complex Boron that supplier a high-dose of boron. Boron plays a critical role in everything from bone metabolism to brain function. It improves cognitive function, and decrease levels of inflammation in the body.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

ATBC, Acetyl Tributyl Citrate is a plasticizer which can easily substitute those plasticizers to be phased out by the EU by February 2015. Actually, one of the main ATBC application is substitution of Phthalates plasticizers (Acetyl Tributyl Citrate is a Phthalate-FREE, bio based plasticizer). ATBC, is a safe, non-toxic plasticizer, biodegradable, mainly used as plasticizer of PVC, cellulose resin and synthetic rubber. Some of its main applications are toys for children, medical products such as blood bags, food packaging materials, and cosmetics; as well as all main PVC compounds, and fixative of inks in the flexographic industry. ATBC is almost colourless and odourless oily liquid, free of foreign materials, insoluble in water but soluble in alcohols and organic solvents. Compared with benzoates plasticizers, ATBC is perfectly odourless. Compared with other Phthalate-FREE plasticizers, ATBC is biodegradable, 100% biobased and it is not a kind of hydrogenated phthalate. Acetyl Tributyl Citrate is recognized as a Safe and Biodegradable plasticizer, with fewer biochemical effects.

Showing 151 - 160 of 391 results