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Details

Stereochemistry RACEMIC
Molecular Formula C8H12O7
Molecular Weight 220.1767
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-ETHYL CITRATE

SMILES

CCOC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

InChIKey=OMPIYDSYGYKWSG-UHFFFAOYSA-N
InChI=1S/C8H12O7/c1-2-15-6(11)4-8(14,7(12)13)3-5(9)10/h14H,2-4H2,1H3,(H,9,10)(H,12,13)

HIDE SMILES / InChI

Molecular Formula C8H12O7
Molecular Weight 220.1767
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

PubMed

PubMed

TitleDatePubMed
The use of dynamic mechanical analysis (DMA) to evaluate plasticization of acrylic polymer films under simulated gastrointestinal conditions.
2010-11
Long-term effect of an ethanol/sodium citrate locking solution on the mechanical properties of hemodialysis catheters.
2010-02-02
Influence of plasticizer type and level on the properties of Eudragit S100 matrix pellets prepared by hot-melt extrusion.
2010
Influence of additives on melt viscosity, surface tension, and film formation of dry powder coatings.
2009-06
A novel concept in enteric coating: a double-coating system providing rapid drug release in the proximal small intestine.
2009-01-19
Stability of dry coated solid dosage forms.
2009
Effect of an ethanol/trisodium citrate hemodialysis catheter locking solution on isolates of Candida albicans.
2008-07
Formulation and statistical optimization of a novel crosslinked polymeric anti-tuberculosis drug delivery system.
2008-06
The manufacture and characterisation of hot-melt extruded enteric tablets.
2008-05
Design and study of ibuprofen disintegrating sustained-release tablets comprising coated pellets.
2008-03
Investigation of the drug release and surface morphological properties of film-coated pellets, and physical, thermal and mechanical properties of free films as a function of various curing conditions.
2008
Preparation and evaluation of diltiazem hydrochloride diffusion-controlled transdermal delivery system.
2008
Effect of ethanol/trisodium citrate lock on microorganisms causing hemodialysis catheter-related infections.
2007-12-29
Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris.
2007-09
Crystal growth formation in melt extrudates.
2007-08-16
[Effects of wheat leaf surface waxes on the feeding of two wheat aphid species].
2007-08
Evaluation of osmotic effects on coated pellets using a mechanistic model.
2007-05-04
The influence of surfactants and additives on drug release from a cationic eudragit coated multiparticulate diltiazem formulation.
2007
Relationship between drug dissolution and leaching of plasticizer for pellets coated with an aqueous Eudragit S100:L100 dispersion.
2006-10-12
Effect of ethanol/trisodium citrate lock on the mechanical properties of carbothane hemodialysis catheters.
2006-05
Morphometrical analysis of multinucleated giant cells in subdermal implants of poly-lactic acid in rats.
2006-05
Physicochemical properties of enteric films prepared from aqueous dispersions and organic solutions.
2006-04-26
The influence of different plasticizers and polymers on the mechanical and thermal properties, porosity and drug permeability of free shellac films.
2006-04
Dry coating in a rotary fluid bed.
2006-02
Influence of plasticizer level on the drug release from sustained release film coated and hot-melt extruded dosage forms.
2006
Temporary restorative resins using non-phthalate ester plasticizers.
2005-08
Quantification of the leaching of triethyl citrate/polysorbate 80 mixtures from Eudragit RS films by differential scanning calorimetry.
2005-05
The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes.
2005-01-26
Antihistamine effects of triprolidine from the transdermal administration of the TPX matrix in rats.
2005-01
"Green" nanocomposites from cellulose acetate bioplastic and clay: effect of eco-friendly triethyl citrate plasticizer.
2004-11-09
Study of triethyl citrate migration from coating polymers to tablet cores.
2004-11
Ethanol/trisodium citrate for hemodialysis catheter lock.
2004-11
Tableting of Eudragit RS and propranolol hydrochloride solid dispersion: effect of particle size, compaction force, and plasticizer addition on drug release.
2004-08
Formulation study for lansoprazole fast-disintegrating tablet. II. Effect of triethyl citrate on the quality of the products.
2003-09
Enhanced film-forming properties for ethyl cellulose and starch acetate using n-alkenyl succinic anhydrides as novel plasticizers.
2003-08
Time-dependent mechanical properties of polymeric coatings used in rupturable pulsatile release dosage forms.
2003-07
Effect of curing conditions and plasticizer level on the release of highly lipophilic drug from coated multiparticulate drug delivery system.
2003
Influence of thermal processing on the properties of chlorpheniramine maleate tablets containing an acrylic polymer.
2002-11
Solid-state plasticization of an acrylic polymer with chlorpheniramine maleate and triethyl citrate.
2002-07-25
The influence of plasticizer on heat-humidity curing of cellulose acetate phthalate coated beads.
2001-11
Laser cutting: influence on morphological and physicochemical properties of polyhydroxybutyrate.
2001-09
Influence of plasticization time, curing conditions, storage time, and core properties on the drug release from Aquacoat-coated pellets.
2001-08
Influence of film additives on stabilizing drug release rates from pellets coated with acrylic polymers.
2001
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:49:30 GMT 2025
Edited
by admin
on Mon Mar 31 21:49:30 GMT 2025
Record UNII
Y7R23627P5
Record Status Validated (UNII)
Record Version
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Name Type Language
CITRIC ACID, 1-ETHYL ESTER
Preferred Name English
1-ETHYL CITRATE
Systematic Name English
1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, 1-ETHYL ESTER
Systematic Name English
(±)-1-ETHYL CITRATE
Systematic Name English
Code System Code Type Description
RXCUI
2587731
Created by admin on Mon Mar 31 21:49:30 GMT 2025 , Edited by admin on Mon Mar 31 21:49:30 GMT 2025
PRIMARY
PUBCHEM
121775
Created by admin on Mon Mar 31 21:49:30 GMT 2025 , Edited by admin on Mon Mar 31 21:49:30 GMT 2025
PRIMARY
FDA UNII
Y7R23627P5
Created by admin on Mon Mar 31 21:49:30 GMT 2025 , Edited by admin on Mon Mar 31 21:49:30 GMT 2025
PRIMARY
DAILYMED
Y7R23627P5
Created by admin on Mon Mar 31 21:49:30 GMT 2025 , Edited by admin on Mon Mar 31 21:49:30 GMT 2025
PRIMARY
CAS
4552-00-5
Created by admin on Mon Mar 31 21:49:30 GMT 2025 , Edited by admin on Mon Mar 31 21:49:30 GMT 2025
PRIMARY