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Restrict the search for
icosapent ethyl
to a specific field?
Status:
Withdrawn
Source:
Metofoline
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
METHOPHOLINE, an isoquinoline derivative, is an opioid analgesic drug. Its (R)-enatiomer is approximately six times more potent than codeine, and (S)-enantiomer is inactive. METHOPHOLINE was withdrawn from the market for reasons of safety.
Status:
Withdrawn
Source:
Genaconazole
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Sch 39304 is a new broad-spectrum orally active triazole antifungal agent that is active, orally and topically, against a broad range of fungal pathogens, including superficial Trichophyton mentagrophytes and vaginal Candida albicans infections. The mechanism of action of SCH-39304 appears similar to those of ketoconazole and fluconazole, involving inhibition of cell membrane ergosterol synthesis. SCH-39304 has two asymmetrical carbon atoms, and the formulation used in clinical trials has been a racemic mixture of two enantiomers, active SCH-42427 (RR (+)-) and inactive SCH-424264 (SS (–)-). Unfortunately, hepatocarcinomas associated with the use of SCH-39304 in animals have sharply restricted the development and use of this agent.
Status:
Withdrawn
Source:
Metofoline
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
METHOPHOLINE, an isoquinoline derivative, is an opioid analgesic drug. Its (R)-enatiomer is approximately six times more potent than codeine, and (S)-enantiomer is inactive. METHOPHOLINE was withdrawn from the market for reasons of safety.
Status:
US Approved Rx
(2019)
Source:
ANDA206455
(2019)
Source URL:
First approved in 1997
Source:
NaturVet ArthriSoothe by The Garmon Corporation
Source URL:
Class:
MIXTURE
Status:
US Approved Rx
(2012)
Source:
ANDA065351
(2012)
Source URL:
First approved in 1991
Source:
CEFZIL by CORDEN PHARMA
Source URL:
Class:
MIXTURE
Targets:
Conditions:
Cefprozil is a 2nd generation cephalosporin that is FDA approved for the treatment of mild to moderate infections of upper respiratory tract, lower respiratory tract, and uncomplicated skin and skin-structure infections. Cefprozil, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Common adverse reactions include diarrhea, nausea, vomiting, dizziness, abdominal pain and vaginitis. Nephrotoxicity has been reported following concomitant administration of aminoglycoside antibiotics and cephalosporin antibiotics. Concomitant administration of probenecid doubled the AUC for cefprozil.
Status:
US Approved Rx
(1955)
Source:
NDA009112
(1955)
Source URL:
First approved in 1949
Source:
EURAX by JOURNEY
Source URL:
Class:
MIXTURE
Conditions:
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use. The drug was approved by FDA for the treatment of scabies and pruritic skin. Crotamiton is a mixture of the cis and trans isomers of N-ethyl-N-(o-methylphenyl)-2butenamide. Although the activity of crotamiton was shown both in vitro and in vivo, the mechanism of its action is still unknown.
Class:
MIXTURE
Broparestrol, (Z)- is an isomer of Broparestrol -- synthetic, nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that has been used in Europe as a dermatological agent and for the treatment of breast cancer. Broparestrol, (Z)- and Broparestrol, (E)- demonstrates antiestrogenic activity but, unlike broparestrol, were never marketed.
Status:
Other
Class:
MIXTURE
Status:
Other
Class:
MIXTURE
Status:
US Approved Allergenic Extract
(1994)
Source:
BLA103738
(1994)
Source URL:
First approved in 1994
Source:
BLA103738
Source URL:
Class:
MIXTURE
Targets:
(E)-Isoeugenol is crystalline while compound with spice clove type odor. The melting point of E-isoeugenol is 33°C. E-Isoeugenol has been shown to cause contact and allergic dermatitis in humans. Positive skin patch tests in numerous individuals have confirmed the sensitizing ability of isoeugenol.
