Glyceryl-1-palmitate (α-Monopalmitin, Glycerol 1-hexadecanoate) is a member of the chemical class known as Monoacylglycerols. Glycerol 1-hexadecanoate is found in fats and oils. Glycerol 1-hexadecanoate is a minor component of olive oil and other vegetable oil. α-Monopalmitin is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides. 1-Palmitoylglycerol may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).

2-Monopalmitin is a monoacylglycerol produced in eukaryotes by lipoprotein lipase (LPL) hydrolysis of triacylglycerols. 2-Monopalmitin may be endogenous ligands for GPR119 receptor