U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 91 - 100 of 2694 results

Status:
Investigational
Source:
USAN:Acetannin
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Acetyltannic acid is an astringent (intestinal) for foals, calves, dogs. It is used for treatment of diarrhoea.
Status:
Investigational
Source:
INN:rifamide
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Rifamides (NSC-143418) are drugs used in the treatment of tuberculosis. They also have immunosuppressive activity, the exact mechanism of which is still unknown, although the ability of rifamides to inhibit tumor necrosis factor (TNF)-induced NF-kB activation may be associated with it. A variety of rifamide analogues exist, such as rifamycin B, rifapentine, rifamycin SV, rifabutin and rifampicin.
Status:
Investigational
Source:
INN:tocofenoxate [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Tocofenoxate is a semisynthetic tocopherol derivative. Vitamin E supplement.
Status:
Investigational
Source:
INN:estrofurate
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Estrofurate (AY-11483) is an impeded estrogen. it prevents ovulation and implantation.
Status:
Investigational
Source:
INN:acetorphine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Acetorphine is a synthetic narcotic analgesic. Acetorphine was reported to have uses in veterinary medicine with pronounced advantages in the immobilization of the giraffe in which toxic effects were reduced as compared to the effects of etorphine. In July 1966, the Director-General of the World Health Organization informed the Secretary-General that WHO had arrived at the conclusion that etorphine and acetorphine should be included in Schedule I of the Convention, since they could give rise to similar abuse, and produce similar ill effects as the substances already listed therein. Acetorphine is a Schedule I controlled substance in the United States.
Status:
Investigational
Source:
INN:nantradol [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Status:
Investigational
Source:
INN:ceftioxide
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Ceftioxide is broad-spectrum , beta-lactam antibiotic patented by German pharmaceutical company Hoechst A.-G.
Status:
Investigational
Source:
INN:dacisteine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Dacisteine is a derivative of a N-acetylcysteine, where a second acetyl group is attached to a sulfur atom. Dacisteine is marketed in France under tradename Mucothiol for the treatment of disorders of bronchial secretion, acute bronchitis and acute episode of chronic bronchopneumopathies. Dacisteine exerts its action on the gel phase of the mucus, presumably by breaking the disulfide bonds of the glycoproteins, and thus promotes the expectoration.
Status:
Investigational
Source:
INN:talosalate
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Talosalate, a phthalidyl ester of acetylsalicylic acid, was used as an analgesic and anti-inflammatory agent. Talosalate was studied in preclinical experiments for the treatment of inflammation and rheumatic disorder in Argentina. However, the further development of the drug appears to have been discontinued.
Status:
Investigational
Source:
USAN:Aceburic Acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Aceburic acid is the acetyl ester of gamma-hydroxybutyrate (GHB), it has analgesic effects as a prodrug to GHB. GHB is used medically as an anesthetic as well as a treatment for several neurologically affecting diseases.